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Can Your HPLC Column Do This?
Comparison of Type-B v. TYPE-C Silica™
A comparison of type B and the evolutionary TYPE-C Silica™ shows that our patented technology extends the
standard growth of spherical silica particle by replacing the hydrogen (H) of the previous surface silanol (O-H)
groups to lay down one additional layer of standard silica, but now with silicon-hydride (H) groups exposed to the
eluent surface instead of Silanol (O-H). This hydride (H) is, compared to silanol groups (O-H), a relatively
non-polar surface with little attraction to water molecules. Changes from aqueous to non aqueous solvents or to
different pH’s in aqueous phases can be made rapidly with little hysteresis (memory effect). TYPE-C™ is a
natural evolution of type B but without many of the adverse effects free silanol groups.
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