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UPHoldC27 HPLC Columns HPLC Column Index


Cogent UPHOLD C27™ HPLC Columns
are designed to provide a unique
separation mechanism for all compounds.
They are particularly useful for retention
of low molecular weight carboxylic acids and other
highly polar compounds which require highly aqueous mobile phase.

Useful with Very High Water Content
Most C18 columns suffer from declining retention over time when used with very high water content mobile phase (>95%). This loss of resolution is due to the “Fold-Back” phenomena which is the compression of the C18 chain caused by lack of

  Consistant Retention in High Aqueous
  Versatile and Rugged
  Useful for Hydrophilic Compounds


wettability. UPHOLD C27™ will give
consistent results longer than C18 phases
in these conditions as the structure of the
stationary phase ligand minimizes folding.

Useful for a Wide Range of Compounds
An increased retention may be found compared with other alkyl based columns and is very useful when increased retention of polar compounds is desired. For many other separations, UPHOLD C27™ can easily be substituted for C18 columns with increased suitability for hydrophilic compounds.

Specifications
Carbon Load: 17%
Particle Shape: 
Pore Size: 120A
pH Range: 2-8
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Click here to compare all Cogent™ Column Specifications


 

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