Pharma‑Grade Syringe Filters for HPLC & Dissolution Testing
Pharma‑grade syringe filters are used for critical HPLC sample preparation and dissolution testing in laboratories operating under GLP, GMP, and regulated quality systems. These filters are designed to deliver consistent, reproducible filtration performance with low extractables and validated compliance, making them ideal for pharmaceutical and regulated analytical workflows.
Compared to general laboratory filters, AQ™ Pharma‑Grade syringe filters are manufactured with enhanced process controls, QC testing, and documented performance, helping reduce variability and protect chromatographic systems.
✅ Why Choose Pharma‑Grade Syringe Filters
No Initial Flush Required (Validated) Eliminates 200 µL or 20 µL discard volumes depending on format, saving time and preventing failed methods
Low Extractables Clean baseline performance for HPLC & UHPLC
Regulatory Compliance Designed to meet FDA CFR Title 21 and USP <788> requirements
Consistent Lot-to-Lot Performance Reduces variability in regulated workflows
Instrument Protection Minimizes particulate contamination to protect columns and detectors
How to Select the Right Syringe Filter
By Membrane Type
Choose based on sample composition and analyte sensitivity:
PVDF – Low protein binding, best for biological samples & mixed solvents
RC (Regenerated Cellulose) – Maximum recovery, very low adsorption for proteins & biomolecules
PP (Polypropylene) – Broad compatibility including acids, bases, aqueous & organic solvents
PTFE – Ideal for organic solvents
Hydrophilic PTFE – Mixed aqueous/organic compatibility
Nylon / PES – General-purpose filtration
By Pore Size
0.45 µm → Sample clarification and prefiltration
0.22 µm → Sterile filtration and fine particulate removal
By Filter Diameter
25 mm → High-throughput, larger sample volumes
13 mm → Routine workflows, moderate volumes
4 mm → Micro-volume and LC‑MS applications (minimal sample loss)
Manufacturing & Quality Controls
AQ™ Pharma‑Grade syringe filters are produced with:
Controlled membrane sourcing and processing
In‑process quality verification
Lot‑to‑lot consistency testing
QC certification with traceability
These controls ensure reliable performance in high-volume and regulated analytical workflows.
Performance Characteristics
Consistent, reproducible filtration performance
Low extractables for clean chromatographic results
Designed for validated analytical methods
Reduced risk of sample loss or adsorption
Reliable operation across high-throughput applications
Typical Applications
HPLC & UHPLC Sample Preparation
Dissolution Testing (USP / FDA methods)
Pharmaceutical QC & Stability Testing
Method Development & Validation
Biological Sample Filtration
Regulated Laboratory Workflows (GLP / GMP)
Formats & Identification
Available in 25 mm, 13 mm, and 4 mm diameters
Color-coded housings by membrane and pore size
Clear labeling for error reduction and workflow efficiency
Additional Resources
