Catalog Number - 82061-PG1-3

Cogent NP Silica™ Wide Pore Guard Column Cartridges are designed to protect valuable analytical HPLC columns from particulate matter, strongly retained contaminants, and sample matrix components that can shorten column life and reduce chromatographic performance. Packed with ultra-high purity, low metal content, 300Å NP Silica™ Wide Pore that remains completely unmodified, these cartridges provide the same chromatographic selectivity as the analytical column they protect while helping maintain method reproducibility and chromatographic efficiency.

82061-PG1-3 is packed with 10 µm NP Silica™ Wide Pore particles in a 2.1 mm ID x 10 mm guard cartridge format. The 300Å pore structure provides improved accessibility for proteins, peptides, biomolecules, and other large molecular weight compounds. Each cartridge is packed in a stainless steel tube and fitted with stainless steel frits pressed into durable PEEK frit caps, providing robust protection for demanding HILIC and Normal Phase applications.

These guard cartridges are especially useful when working with complex samples that may contain particulate matter or strongly retained compounds. Regular replacement of guard cartridges can significantly extend analytical column lifetime, preserve chromatographic performance, and reduce operating costs while protecting valuable NP Silica™ Wide Pore analytical columns.

Key Benefits

• NP Silica™ Wide Pore stationary phase

• USP L3 equivalent chemistry

• Ultra-high purity silica

• Low metal content silica

• Unmodified silica surface

• 300Å wide pore design

• 10 µm particle size

• Protects analytical columns from contamination

• Helps extend analytical column life

• Maintains chromatographic performance

Typical Applications

• Analytical HPLC

• Protein analysis

• Peptide analysis

• Biomolecule separations

• Large molecule analysis

• HILIC chromatography

• Normal Phase chromatography

• Pharmaceutical analysis

• Method development

• Column protection

Specifications

• Product Type: Guard Column Cartridge

• Stationary Phase: NP Silica™ Wide Pore

• USP Classification: L3

• Chromatography Modes: HILIC and Normal Phase

• Particle Size: 10 µm

• Pore Size: 300Å

• Cartridge Dimensions: 2.1 mm ID x 10 mm

• Cartridge Material: Stainless Steel

• Frit Material: Stainless Steel with PEEK Frit Caps

• Pack Size: 5/PK

• Brand: Cogent

Guard Column Holder Required

• Requires the Cogent Guard Column Holder for 2.1 mm ID Guard Column Cartridges (Catalog Number 83200-GH) for installation and operation.

Important Notes

• Suitable for HILIC and Normal Phase chromatography

• USP L3 equivalent stationary phase

• Unmodified silica surface chemistry

• Manufactured from ultra-high purity, low metal content silica

• 300Å wide pore structure provides improved accessibility for proteins, peptides, and other large molecules

• Designed to protect NP Silica™ Wide Pore analytical columns from particulates and strongly retained contaminants

• Helps extend analytical column service life

• Maintains chromatographic performance and reproducibility

• Recommended for routine analytical and method development applications

• Compatible with 2.1 mm ID NP Silica™ Wide Pore analytical columns

• Requires the Cogent Guard Column Holder (83200-GH)

• Packaged as 5 guard cartridges per package

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