Catalog Number - 58045-CA13-K

The 58045-CA13-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Cellulose Acetate (CA) membrane, these filters provide consistent performance, low extractables, and reliable chromatographic results.

Cellulose Acetate membranes are naturally hydrophilic and surfactant-free, eliminating extractable contaminants common in many hydrophilic filters. With very low protein binding, they are ideal for biological and aqueous samples where maximum recovery is critical.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

• US FDA CFR Title 21, Part 211.92 – minimum fiber release

• USP <788> – particulate matter in injectables

• USP “Sterile Water for Injection”

Benefits:

• ✅ No initial flushing required

• ✅ No 200 µL discard required

• ✅ Improves recovery and efficiency

• ✅ Reduces risk of failed methods

Performance & Design

The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering high flow rates and reduced clogging.

The 13 mm format is ideal for low to moderate sample volumes, while the 1000/case packaging supports high-throughput laboratories and production workflows.

CA membranes excel in aqueous and biological applications, where low protein binding and clean baselines are essential.

The orange housing ensures easy identification, and each case includes a Certificate of Analysis.

Key Features

0.45 µm Cellulose Acetate Membrane (Pharma Grade)

• Ideal for aqueous and biological samples

• Surfactant-free, low extractables

✅ No Initial Flush Required (Validated)

• No 200 µL discard required

Low Protein Binding

• Maximizes analyte recovery

Hydrophilic Membrane

• No pre-wetting required

Optimized Volume (13 mm)

• Efficient filtration with reduced waste

Bulk Packaging (1000/Case)

• Reduces cost per analysis

• Ideal for high-volume workflows

Regulatory Compliance

• FDA CFR 21 (211.92), USP <788>

Color-Coded (Orange)

• Identifies CA filters

Typical Applications

• HPLC & UHPLC Sample Preparation – aqueous sample clarification

• Biological Samples – protein / biomolecule filtration

• Dissolution Testing – pharmaceutical QC

• Buffers & Media Filtration

• High-Throughput Laboratories – consistent performance

Specifications

• Membrane Material: Cellulose Acetate (CA)

• Pore Size: 0.45 µm

• Diameter: 13 mm

• Housing: Polypropylene (PP)

• Color Code: Orange

• Protein Binding: Low

• Hydrophilicity: Hydrophilic

• Extractables: None detectable (no flush required)

• Sterilization: Autoclave or EO

• Compliance: FDA CFR 21, USP <788>

• Pack Size: 1000/Case

• Brand: AQ™

Resources & Ordering Options

• Purchase Cellulose Acetate syringe filters, 0.45 µm, 13 mm – 50/pack quantity

• Order Cellulose Acetate syringe filters, 0.45 µm, 13 mm – 100/pack quantity