CUSTOM ITEM: Adapter, for use with Low to Medium Pressure HPLC. 10-32 female to 1/4"-28 female connection, 0.25 mm bore size. PEEK. ARE-Applied Research brand. Bulk Pricing
Additional Info:
The 47450‑05 PEEK HPLC Adapter is a precision fluidic connection fitting designed for low‑ to medium‑pressure HPLC applications. This adapter converts standard 10‑32 female inlet threading to 1/4‑28 female column threading, providing secure and reliable integration between tubing connections and PEEK column hardware systems.
Engineered with a 0.25 mm internal bore, this adapter supports low dead‑volume flow paths, helping maintain chromatographic efficiency, peak shape, and reproducibility.
Manufactured from high-performance PEEK (polyether ether ketone), this fitting ensures a fully bioinert flow path, eliminating unwanted interactions with metal surfaces. It is ideal for proteins, peptides, nucleic acids, ions, and metal‑sensitive compounds, where maintaining analyte integrity is critical.
✅ Key Benefits
Thread Conversion (10‑32 to 1/4‑28) Enables compatibility between standard tubing and PEEK column systems
Low Dead‑Volume Design (0.25 mm Bore) Minimizes dispersion and preserves chromatographic efficiency
True Bioinert Flow Path Eliminates metal interaction for sensitive analytes
Optimized for PEEK Column Hardware Ensures seamless integration with All‑PEEK column systems
Reliable Sealing & Connection Stability Maintains consistent flow and pressure performance
Performance & Design
This adapter is precision machined from PEEK, providing:
High chemical resistance across common HPLC solvents
Mechanical strength for repeated use
Stable performance in low‑ and medium‑pressure systems
The 0.25 mm bore size is specifically designed to:
Reduce extra-column volume
Maintain sharp peaks
Improve system efficiency in analytical workflows
System Role & Integration
This adapter is used to connect:
10‑32 threaded tubing (standard HPLC inlet connections)
1/4‑28 threaded PEEK column bodies (2.1 mm ID systems)
It plays a critical role in:
Column packing setups
Custom column configurations
Bioinert chromatography systems
⚠️ Usage Guidance
Designed for use with All‑PEEK HPLC column hardware systems
Not recommended for use with stainless steel columns, where material mismatch may affect sealing or performance
Typical Applications
HPLC & UHPLC System Connections (low to medium pressure)
PEEK Column Packing & Assembly
Bioanalytical Workflows (metal‑sensitive analytes)
LC‑MS Compatible Configurations
Custom Fluid Path Design
Use Case Positioning
Fluidic Interface & Connection Component
Bridges tubing systems and PEEK column hardware
Enables flexible system configuration
Supports low dead‑volume, high‑performance chromatography
Specifications
Product Type: HPLC Adapter / End Fitting
Material: PEEK (Polyether Ether Ketone)
Connection 1: 10‑32 Female
Connection 2: 1/4‑28 Female
Internal Bore: 0.25 mm
Pressure Range: Low to Medium Pressure HPLC
Flow Path: Bioinert / metal‑free
Compatibility: All‑PEEK column systems (2.1 mm ID)
Brand: ARE‑Applied Research™
Packaging: Bulk (Custom Item)
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