Syringe Filters, 13mm, PES, 0.22um Pore Size. White/Orange Polypropylene, AQ Brand. 1000/CS.
Additional Info:
The 58022-PES13-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput membrane filters engineered for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Polyethersulfone (PES) membrane, these filters deliver exceptional consistency, ultra-low protein binding, and extractable-free performance, ensuring maximum sample purity and reproducible analytical results in high-volume workflows.
The 13 mm format is optimized for low sample volume applications, providing efficient filtration with minimal hold-up volume, making these filters ideal for protein solutions, buffers, and biological samples where recovery and sample conservation are critical.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet stringent regulatory requirements, including:
US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Preserves valuable samples—critical for low-volume workflows
✅ Eliminates a common source of failed methods and costly investigations
👉 This delivers a major operational and compliance advantage for QC/QA and biopharma laboratories, especially in regulated, high-throughput environments where reproducibility and efficiency are essential.
Performance & Design
The 0.22 µm PES membrane is optimized for sterile filtration and fine particulate removal, ensuring maximum clarity and protection of analytical systems.
PES membrane chemistry provides ultra-low protein binding, low extractables, and excellent flow characteristics, ensuring maximum recovery of proteins and sensitive biomolecules, even in small-volume applications.
The 13 mm design minimizes hold-up volume, maximizing recovery from limited or high-value samples, making these filters ideal for method development, LC-MS workflows, and precision analytical applications.
The white housing with orange lettering allows rapid identification of 0.22 µm PES filters, and each case includes a Certificate of Analysis for full traceability and compliance.
Key Features
0.22 µm PES Membrane (Pharma Grade)
Ideal for sterile filtration and fine particulate removal
Ensures maximum sample clarity and system protection
✅ No Initial Flush Required (Validated)
Extractable-free from first filtrate
No 200 µL discard required
Ultra-Low Protein Binding
Maximizes recovery of proteins and biomolecules
Ideal for biopharma and biological samples
Optimized for Low Sample Volumes (13 mm)
Minimizes hold-up volume
Ideal for high-value or limited samples
High Throughput Performance
Fast filtration with minimal resistance
Suitable for high-volume workflows
Low Extractables
Ensures clean chromatographic baselines
Improves reproducibility
Absolute Retention
Reliable sterile filtration performance
Suitable for critical analytical methods
Regulatory Compliance
Meets FDA CFR Title 21 requirements
Complies with USP <788>
Suitable for Sterile Water for Injection
Autoclavable & EO Sterilizable
121°C for 30 minutes or Ethylene Oxide
Color-Coded (White / Orange)
Identifies 0.22 µm PES filters
Bulk Packaging (1000/Case)
Reduces cost per analysis
Ideal for high-throughput QC environments
Typical Applications
HPLC & UHPLC Sample Preparation – fine particulate removal prior to injection
Sterile Filtration – bacterial and contaminant removal
Protein & Biomolecule Filtration – low binding, high recovery
Cell Culture Media & Buffers – clean and efficient filtration
Method Development – limited or high-value samples
Dissolution Testing – pharmaceutical QC workflows
High-Throughput Laboratories – consistent, efficient performance
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: PES (Polyethersulfone)
Pore Size: 0.22 µm
Diameter: 13 mm
Housing Material: Polypropylene (PP)
Color Code: White / Orange (0.22 µm PES)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Aqueous solutions, buffers, biological samples
Protein Binding: Ultra-low
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 1000/Case
Brand: AQ™
Resources & Ordering Options
Order PES syringe filters, 0.22 µm, 13 mm – 100/pack quantity
Purchase PES syringe filters, 0.22 µm, 13 mm – 50/pack quantity