Syringe Filters, 13mm, Nylon, 0.45um Pore Size. Green Polypropylene, AQ Brand. 100/PK.

Additional Info:

The 58045-N13-C AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Nylon‑66 membrane, these filters provide exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring reliable and reproducible chromatographic results.

The 13 mm format is optimized for low sample volume applications, allowing efficient filtration while minimizing sample loss—ideal for analytical labs and method development workflows where sample conservation is critical.


✅ Critical Compliance Advantage (No Flush Required)

These filters are validated and certified to meet stringent regulatory requirements, including:

  • US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release

  • USP <788> for particulate matter in injectables

  • USP requirements for “Sterile Water for Injection”

Because of this validated performance:

  • ✅ No initial flushing is required

  • ✅ No need to discard the first 200 µL of filtrate

  • ✅ Preserves valuable samples (especially critical for small volumes)

  • ✅ Saves time and reduces risk of failed methods and investigations

👉 This creates a significant operational and compliance advantage for QC/QA laboratories, where efficiency, traceability, and method reliability are essential.


Performance & Design

The 0.45 µm pore size is ideal for sample clarification and prefiltration, offering high flow rates with reduced clogging, improving analytical efficiency.

Nylon‑66 membrane chemistry ensures broad compatibility with aqueous and organic HPLC solvents, while maintaining ultra-low adsorption—even for charged analytes, supporting accurate quantitation.

Engineered for low-volume workflows, the 13 mm design minimizes hold-up volume and sample waste, making it an excellent choice for limited or high-value samples.

The green color coding allows rapid identification of 0.45 µm nylon filters, and each pack includes a Certificate of Analysis for full compliance and traceability.


Key Features

0.45 µm Nylon‑66 Membrane (Pharma Grade)

  • Ideal for clarification and prefiltration

  • High consistency for validated analytical methods

✅ No Initial Flush Required (Validated)

  • Extractable-free from first filtrate

  • Eliminates sample waste and variability

Ultra-Low Adsorption

  • Suitable for charged and sensitive analytes

  • Maximizes analyte recovery

Optimized for Low Sample Volumes (13 mm)

  • Minimizes sample loss

  • Ideal for analytical and method development work

Regulatory Compliance

  • Meets FDA CFR Title 21 requirements

  • Complies with USP <788>

  • Suitable for Sterile Water for Injection

Broad Solvent Compatibility

  • Compatible with aqueous and organic HPLC solvents

  • Ideal for mixed solvent systems

Autoclavable & EO Sterilizable

  • 121°C for 30 minutes or Ethylene Oxide

Color-Coded (Green)

  • Identifies 0.45 µm nylon filters


Typical Applications

  • HPLC & UHPLC Sample Preparation – small-volume sample clarification

  • Dissolution Testing – pharmaceutical QC workflows

  • Method Development – limited or valuable sample handling

  • Regulated Laboratory Methods – validated, compliant processes

  • Pharmaceutical Analysis – injectables and formulations

  • Aqueous & Organic Filtration – mixed solvent compatibility


Specifications

  • Filter Type: Syringe Filter (Pharma Grade)

  • Membrane Material: Nylon‑66

  • Pore Size: 0.45 µm

  • Diameter: 13 mm

  • Housing Material: Polypropylene (PP)

  • Color Code: Green (0.45 µm Nylon)

  • Connection Type: Luer Lock / Slip

  • Chemical Compatibility: Aqueous and organic solvents

  • Extractables: None detectable (no flush required)

  • Sterilization: Autoclave or EO

  • Compliance: FDA CFR 21, USP <788>

  • Certification: Certificate of Analysis included

  • Sterility: Non-sterile

  • Pack Size: 100/PK

  • Brand: AQ™


Resources & Ordering Options

 

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