Syringe Filters, 25mm, Nylon, 0.45um Pore Size. Green Polypropylene, AQ Brand. 50/PK.
Additional Info:
The 58045-N25-A AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring accurate and reproducible analytical results—even in high-throughput workflows.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet strict regulatory requirements, including:
US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Eliminates wasted sample and saves time
✅ Reduces risk of failed methods and costly investigations
👉 This provides a significant operational and compliance advantage for QC/QA laboratories, where reproducibility, documentation, and efficiency are critical.
Performance & Design
The 0.45 µm pore size is ideal for sample clarification and prefiltration, offering high flow rates with reduced clogging compared to finer membranes.
The advanced 16-channel outlet design minimizes back pressure, allowing smooth filtration with less hand force, improving ergonomics and throughput during routine use.
Nylon‑66 membrane chemistry provides broad compatibility with aqueous and organic solvents, while maintaining low adsorption even for charged analytes, ensuring reliable quantitation.
The 25 mm format supports higher sample volumes, and the green color coding allows easy identification of 0.45 µm nylon filters.
Each pack is supplied with a Certificate of Analysis, ensuring traceability and compliance.
Key Features
0.45 µm Nylon‑66 Membrane (Pharma Grade)
Ideal for clarification and prefiltration
High consistency for validated methods
✅ No Initial Flush Required (Validated)
Zero extractables from first drops
Eliminates sample waste and variability
Ultra-Low Adsorption
Suitable for charged and sensitive analytes
Maximizes recovery
Advanced 16-Channel Outlet Design
Reduces back pressure
Requires less hand force
Regulatory Compliance
FDA CFR Title 21 compliant
Meets USP <788>
Suitable for Sterile Water for Injection
Broad Solvent Compatibility
Aqueous and organic HPLC solvents
Mixed solvent systems
25 mm Diameter for High Throughput
Handles larger volumes
Improves lab productivity
Autoclavable & EO Sterilizable
121°C or Ethylene Oxide
Color-Coded (Green)
Identifies 0.45 µm nylon
Typical Applications
HPLC & UHPLC Sample Preparation – reliable clarification before injection
Dissolution Testing – pharmaceutical QC and release testing
Regulated Methods – compliant workflows without variability
Pharmaceutical Analysis – injectables and formulations
Aqueous & Organic Filtration – mixed solvent compatibility
High-Throughput QC Labs – consistent, repeatable performance
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: Nylon‑66
Pore Size: 0.45 µm
Diameter: 25 mm
Housing Material: Polypropylene (PP)
Color Code: Green (0.45 µm Nylon)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Aqueous and organic solvents
Extractables: None detectable (no flush required)
Sterilization: Autoclavable or EO
Compliance: FDA CFR 21, USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 50/PK
Brand: AQ™
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