Syringe Filters, 13mm, PTFE, 0.45um Pore Size. Yellow Polypropylene, AQ Brand. 50/PK.
Additional Info:
The 58045-P13-A AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm PTFE (Polytetrafluoroethylene) membrane, these filters provide exceptional chemical resistance, high flow performance, and extractable-free filtration, ensuring reliable and reproducible chromatographic results.
PTFE membranes are the preferred choice for organic solvent systems, offering superior durability and compatibility with aggressive solvents, acids, and bases, making them ideal for demanding analytical workflows.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet stringent regulatory requirements, including:
US FDA CFR Title 21, Part 211.92 for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Preserves valuable samples
✅ Eliminates a common source of failed methods and investigations
👉 This provides a strong operational and compliance advantage for QC/QA laboratories, particularly when working with costly organic solvents or regulated methods.
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering high flow rates and reduced clogging, ideal for routine analytical workflows.
PTFE membrane chemistry provides maximum chemical compatibility, ensuring reliable performance in organic solvents, strong acids, and alkaline conditions, without degradation.
⚠️ Important: PTFE membranes are hydrophobic and not recommended for 100% aqueous or buffer solutions, making them best suited for organic or mixed solvent systems.
The 13 mm format is optimized for low to moderate sample volumes, providing efficient filtration while minimizing waste, making it suitable for routine lab work and sample-limited applications.
The yellow housing enables quick identification of 0.45 µm PTFE filters, and each pack includes a Certificate of Analysis for full traceability and compliance.
Key Features
0.45 µm PTFE Membrane (Pharma Grade)
Ideal for organic solvent filtration
High chemical resistance and durability
✅ No Initial Flush Required (Validated)
Extractable-free from first filtrate
No 200 µL discard required
Superior Chemical Resistance
Compatible with solvents, acids, and bases
Will not degrade under harsh conditions
⚠️ Hydrophobic Membrane
Not suitable for 100% aqueous solutions
Designed for organic or mixed-phase applications
Optimized for Moderate Volumes (13 mm)
Efficient filtration with reduced waste
Suitable for routine applications
Low Extractables
Clean chromatographic baselines
Improves reproducibility
Regulatory Compliance
Meets FDA CFR 21 (211.92) requirements
Complies with USP <788>
Suitable for Sterile Water for Injection
Color-Coded (Yellow)
Identifies 0.45 µm PTFE filters
Typical Applications
HPLC & UHPLC Sample Preparation – organic solvent filtration
Pharmaceutical Analysis – dissolution and QC workflows
Organic & Chemical Analysis – aggressive solvent systems
Environmental Testing – non-aqueous samples
Routine Laboratory Workflows – moderate sample volumes
Regulated Laboratory Methods – validated, compliant processes
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: PTFE (Polytetrafluoroethylene)
Pore Size: 0.45 µm
Diameter: 13 mm
Housing Material: Polypropylene (PP)
Color Code: Yellow (0.45 µm PTFE)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Organic solvents, acids, bases
Hydrophilicity: Hydrophobic (not for aqueous solutions)
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21 (211.92), USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 50/PK
Brand: AQ™
Resources & Ordering Options
Purchase PTFE syringe filters, 0.45 µm, 13 mm – 100/pack quantity
Order PTFE syringe filters, 0.45 µm, 13 mm – 1000/case quantity