Syringe Filters, 13mm, RC, 0.45um Pore Size. Brown Polypropylene, AQ Brand. 100/PK.

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Additional Info:

The 58045-R13-C AQ™ Syringe Filters are pharmaceutical-grade regenerated cellulose (RC) membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm regenerated cellulose membrane, these filters provide low extractables, excellent analyte recovery, and consistent chromatographic performance.

Regenerated cellulose membranes offer very low protein binding and low hold-up volume, making them ideal for protein solutions, buffers, and cell culture media, especially when maximum recovery of analytes is critical.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

  • US FDA CFR Title 21, Part 211.92 – minimum fiber release

  • USP <788> – particulate matter in injectables

  • USP “Sterile Water for Injection”

Benefits:

  • ✅ No initial flushing required

  • ✅ No 200 µL discard required

  • ✅ Improves recovery and efficiency

  • ✅ Reduces risk of failed methods


Performance & Design

The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering reliable particulate removal and consistent flow.

The RC membrane provides low adsorption and high recovery, making it ideal for biological and aqueous workflows.

The 13 mm format is designed for low to moderate sample volumes, minimizing sample waste while maintaining efficient filtration.

Not recommended for use with strong acids or bases.

The brown housing allows quick identification, and each pack includes a Certificate of Analysis.


Key Features

0.45 µm Regenerated Cellulose Membrane (Pharma Grade)

  • Very low protein binding

  • Ideal for biological and aqueous samples

✅ No Initial Flush Required (Validated)

  • No 200 µL discard required

Low Hold-Up Volume

  • Maximizes analyte recovery

Optimized Volume (13 mm)

  • Efficient filtration with reduced waste

Low Extractables

  • Clean chromatographic results

Biological Compatibility

  • Suitable for proteins, buffers, and media

Regulatory Compliance

  • FDA CFR 21 (211.92), USP <788>

Color-Coded (Brown)

  • Identifies RC filters


Typical Applications

  • HPLC & UHPLC Sample Preparation – aqueous filtration

  • Protein & Biomolecule Samples – maximum recovery

  • Cell Culture Media & Buffers

  • Dissolution Testing – pharmaceutical QC

  • Routine Analytical Workflows


Specifications

  • Membrane Material: Regenerated Cellulose (RC)

  • Pore Size: 0.45 µm

  • Diameter: 13 mm

  • Housing: Polypropylene (PP)

  • Color Code: Brown

  • Protein Binding: Very Low

  • Hydrophilicity: Hydrophilic

  • Extractables: None detectable (no flush required)

  • Chemical Compatibility: Aqueous solutions (avoid strong acids/bases)

  • Sterilization: Autoclave or EO

  • Compliance: FDA CFR 21, USP <788>

  • Pack Size: 100/PK

  • Brand: AQ™


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