Syringe Filters, 25mm, PVDF, 0.45um Pore Size. Red Polypropylene, AQ Brand. 100/PK.
Additional Info:
The 58045-V25-C AQ™ Syringe Filters are pharmaceutical-grade PVDF membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm polyvinylidene fluoride (PVDF) membrane, these filters provide low extractables, broad chemical compatibility, and consistent chromatographic performance.
PVDF membranes offer low protein binding and excellent compatibility with both aqueous and organic solvents, making them ideal for biological samples and high-purity analytical workflows.
✅ Critical Compliance Advantage (No Flush Required)
Validated to meet key regulatory standards:
US FDA CFR Title 21, Part 211.92 – minimum fiber release
USP <788> – particulate matter in injectables
USP “Sterile Water for Injection”
Benefits:
✅ No initial flushing required
✅ No 200 µL discard required
✅ Extractable-free from first filtrate
✅ Reduces risk of failed methods
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering reliable flow and particulate removal.
The PVDF membrane combines low protein binding with strong chemical resistance, supporting use with buffers, biological samples, and mixed solvent systems.
The 25 mm format supports larger sample volumes, making it ideal for routine and high-throughput workflows.
The red housing allows quick identification, and each pack includes a Certificate of Analysis.
Key Features
0.45 µm PVDF Membrane (Pharma Grade)
Low protein binding
Suitable for aqueous and organic samples
✅ No Initial Flush Required (Validated)
No 200 µL discard required
Broad Chemical Compatibility
Compatible with buffers and solvents
Low Extractables
Clean chromatographic baselines
Biological Compatibility
Ideal for protein and biomolecule samples
High Throughput (25 mm)
Handles larger sample volumes
Regulatory Compliance
FDA CFR 21 (211.92), USP <788>
Color-Coded (Red)
Identifies PVDF filters
Typical Applications
HPLC & UHPLC Sample Preparation – general-purpose filtration
Biological Samples – protein and biomolecule work
Dissolution Testing – pharmaceutical QC
Buffers & Mixed Solvent Systems
Routine Analytical Workflows
Specifications
Membrane Material: Polyvinylidene Fluoride (PVDF)
Pore Size: 0.45 µm
Diameter: 25 mm
Housing: Polypropylene (PP)
Color Code: Red
Protein Binding: Low
Chemical Compatibility: Aqueous & organic solvents
Extractables: None detectable (no flush required)
Membrane Thickness: 135 µm (±15 µm)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Pack Size: 100/PK
Brand: AQ™
Resources & Ordering Options
Purchase PVDF syringe filters, 0.45 µm, 25 mm – 50/pack quantity
Order PVDF syringe filters, 0.45 µm, 25 mm – 1000/case quantity