Prep HPLC Column, Bidentate C18, 4um, 100A. 30mm ID x 150mm Length. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑P30‑150 Cogent Bidentate C18™ Preparative HPLC Column is a large‑diameter, long‑format preparative column engineered for purification workflows that require both very high loading capacity and enhanced resolving power. Built on Cogent TYPE‑C™ silica hydride technology, this column delivers excellent selectivity, rapid equilibration, and very robust column lifetimes across demanding preparative methods.
The stationary phase features an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This chemistry creates a phase that is highly hydrophobic yet versatile, providing strong and stable retention of hydrophobic molecules, metabolites, and amine‑containing analytes. Unlike conventional silica‑based prep C18 columns, the TYPE‑C™ hydride surface remains stable in aqueous‑dominant mobile phases and tolerates low‑pH conditions, expanding method flexibility for preparative separations.
With a 30 mm internal diameter and an extended 150 mm length, this column offers substantially increased plate count compared with 30 × 50 mm and 30 × 100 mm formats, making it well suited when closely eluting components must be resolved while processing large sample loads.
System Note: A specialized preparative HPLC system (sufficient high‑flow pump capacity, appropriate tubing/valving, injector, and fraction‑collection hardware) is required for columns of this size and length.
Why Choose the 30 × 150 mm Prep Bidentate C18™ Format
This configuration is typically selected when:
Preparative runs require higher resolution than 30 × 100 mm columns can provide
Large sample loads include closely related impurities or structural analogs
Hydrophobic or basic analytes challenge traditional prep C18 materials
Higher purity fractions are required without moving to the longest (250 mm) format
The longer length increases interaction time and selectivity, while TYPE‑C™ silica hydride chemistry maintains fast equilibration and long service life even under aggressive preparative conditions.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Reduced silanol activity and secondary interactions
Faster equilibration than conventional preparative C18 columns
Very robust lifetimes for repeated purification cycles
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Strong, stable hydrophobic retention
Particularly effective for hydrophobic and amine‑containing analytes
Preparative Geometry with Enhanced Resolution
30 mm ID × 150 mm length
Increased plate count vs. shorter 30 mm formats
Supports tighter fraction cuts at high mass loadings
Broad Operating Window
Compatible with aqueous‑dominant mobile phases
Stable under low‑pH conditions
Tolerates aggressive purification methods
Typical Applications
Preparative purification with high sample loads
Resolution of closely eluting compounds at prep scale
Hydrophobic molecule and metabolite isolation
Amine‑containing analytes
Scale‑up from analytical or smaller preparative columns
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable