Guard Column Kit, PEEK, 3.0 mm ID, 8 mm active length. ARE-Applied Research brand. 1 EA.

Additional Info:

The 49330‑GC1 All‑PEEK Guard Column Kit is designed for protecting analytical and semi‑analytical HPLC columns while maintaining a fully bioinert flow path. This complete kit includes the guard column holder and replaceable cartridge components, providing a convenient solution for extending column life in demanding applications.

Constructed entirely from PEEK (polyether ether ketone), including the frits, this system ensures a completely metal‑free environment, eliminating unwanted interactions between analytes and stainless steel surfaces. This is critical for proteins, peptides, nucleic acids, ions, and metal‑sensitive compounds, where adsorption or catalytic effects can impact recovery and data quality.

✅ Why Use a PEEK Guard Column Kit

  • Protects Analytical Columns Prevents particulates and contaminants from reaching the main column

  • True Bioinert Flow Path Eliminates metal interaction for sensitive analytes

  • Improves Column Lifetime Reduces fouling and extends column usability

  • Maintains Chromatographic Integrity Minimizes adsorption and preserves peak shape

  • Replaceable Cartridge Design Enables easy maintenance and cost control


Performance & Design

The guard column components are manufactured using a proprietary extrusion process that creates a smooth, mirror‑like internal surface, supporting:

  • Minimal band broadening

  • Low dispersion

  • Consistent flow characteristics

All wetted components—including tube and frits—are made from extruded PEEK, ensuring:

  • No chemical coatings or treatments

  • Uniform surface chemistry

  • Reliable bioinert performance

Carbon is incorporated into the formulation of the black components prior to extrusion, enhancing durability without altering surface chemistry.


Included Components

  • 3.0 mm ID All‑PEEK guard column body (8 mm active length)

  • 2 × PEEK frits

  • Guard column holder (included)


Use Case Positioning

3.0 mm ID / 8 mm Active Length Guard Column

  • Designed for protecting analytical 3.0 mm and 4.6 mm ID columns

  • Ideal for routine HPLC workflows and bioanalytical methods

  • Minimizes system contamination while preserving performance


Typical Applications

  • HPLC & UHPLC Column Protection

  • Protein & Biomolecule Analysis

  • Pharmaceutical QC and Method Development

  • Routine Analytical Workflows

  • LC‑MS Applications requiring metal‑free flow paths


⚠️ When to Use a PEEK Guard Column

Use a guard column when:

  • Samples contain particulates or matrix contaminants

  • Working with sensitive analytes prone to metal interaction

  • Extending the lifetime of expensive analytical columns is critical


System Requirements

The Cogent Guard Column Holder is included in this kit and required for use


Specifications

  • Product Type: Guard Column Kit

  • Material: All‑PEEK (including frits)

  • Internal Diameter: 3.0 mm

  • Active Length: 8 mm

  • Frit Material: PEEK

  • Flow Path: Metal‑free (bioinert)

  • Surface Treatment: None (extrusion-based finish only)

  • Holder: Included

  • Brand: ARE‑Applied Research™

  • Unit: 1 Each

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