CUSTOM ITEM: End Fitting, PEEK, for 4.6 mm ID columns, ARE-Applied Research brand. Bulk Price.

Additional Info:

The 49333‑EF4 PEEK End Fitting is a precision-machined connection component designed specifically for 4.6 mm ID All‑PEEK HPLC column hardware systems. This fitting provides the critical interface between standard HPLC tubing and PEEK column bodies, ensuring secure, leak‑free operation and consistent chromatographic performance.

This end fitting features a dual-thread configuration:

  • 10‑32 female thread (tubing inlet)

  • 1/2‑20 column thread (column body connection)

Manufactured from high-performance PEEK (polyether ether ketone), this component maintains a fully bioinert, metal‑free flow path, preventing interactions with sensitive analytes.

✅ Key Benefits

  • Critical Column Interface Component Connects tubing to 4.6 mm ID PEEK column bodies

  • True Bioinert Flow Path (PEEK Construction) Eliminates metal interaction for sensitive compounds

  • Secure, Leak‑Free Connection Maintains system pressure and chromatographic integrity

  • Compatible with Standard HPLC Threading 10‑32 inlet and 1/2‑20 column connection

  • Optimized for All‑PEEK Column Systems Ensures consistent system performance


Performance & Design

This end fitting is precision machined from PEEK, providing:

  • Excellent chemical resistance to common HPLC solvents

  • Mechanical durability for repeated assembly and use

  • Stable sealing performance under low‑to‑moderate pressure conditions

The design ensures:

  • Proper alignment between tubing and packed column bed

  • Reduced risk of leakage or misalignment

  • Consistent flow path performance


System Role & Integration

This component is essential for:

  • HPLC column assembly and packing workflows

  • Final column configuration and sealing

  • Maintaining bioinert fluid path continuity

It connects:

  • 10‑32 threaded HPLC tubing

  • 1/2‑20 threaded 4.6 mm ID column body tubes


⚠️ Usage Guidance

  • Designed specifically for All‑PEEK HPLC column hardware systems

  • Not recommended for use with stainless steel columns, as mixed-material systems may affect sealing performance and analyte interaction


Typical Applications

  • HPLC Column Packing & Assembly

  • Custom Column Development

  • Bioanalytical Workflows (metal‑sensitive analytes)

  • Protein, Peptide, and Nucleic Acid Separations

  • Pharmaceutical Method Development and QC

  • LC‑MS Compatible Systems


Use Case Positioning

Column Hardware Connection Component

  • Essential for building and maintaining PEEK HPLC columns

  • Ensures reliable, leak‑free system operation

  • Supports bioinert chromatography workflows


Specifications

  • Product Type: End Fitting / Column Connection Component

  • Material: PEEK (Polyether Ether Ketone)

  • Connection 1: 10‑32 Female (tubing inlet)

  • Connection 2: 1/2‑20 (column tube thread)

  • Compatible Column ID: 4.6 mm

  • Flow Path: Bioinert / metal‑free

  • Pressure Range: Low to Medium Pressure HPLC

  • Compatibility: All‑PEEK column systems

  • Brand: ARE‑Applied Research™

  • Packaging: Bulk (Custom Item)

Resource Options

Custom Order Item. Inquire for more information.

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