HPLC Column Set, PEEK with a 4.6 mm ID. Includes, a 300 mm x 4.6 mm black, column body tube (1/2-20 threads), plus 2 PEEK 2 um frits & 2 end fittings. ARE-Applied Research brand. 1 EA.
Additional Info:
The 49335‑300 All‑PEEK HPLC Column Set is designed for professional column packers and advanced chromatographers who require maximum separation power and complete control over bioinert column construction. The 300 mm length configuration provides extended retention, increased peak capacity, and the highest achievable resolution within analytical-scale column formats.
PEEK (polyether ether ketone) column hardware provides a completely metal‑free flow path, eliminating interactions that can occur between analytes and stainless steel surfaces. This is especially important for proteins, peptides, nucleic acids, ions, and metal‑sensitive compounds, where adsorption or catalytic effects can reduce recovery and compromise data quality.
✅ Why Choose All‑PEEK Column Hardware
True Bioinert Flow Path Eliminates metal contact for sensitive analytes
Maximum Recovery & Peak Fidelity Reduces adsorption and preserves analyte integrity
Pack Any Stationary Phase Full flexibility for custom column development
Reusable & Repackable Design Ideal for advanced R&D and method validation
Standard 1/2‑20 Thread Format Compatible with common 4.6 mm column packing systems
Performance & Design
The column body is manufactured using a proprietary extrusion process that produces a smooth, mirror‑like internal surface, enabling:
Highly uniform and reproducible packing
Reduced turbulence and flow inconsistencies
Maximum chromatographic efficiency
This hardware is constructed from graphite-filled PEEK, where graphite is incorporated prior to extrusion, not added as a coating.
Key advantages:
No chemical surface treatments
Consistent internal surface chemistry
Durable black exterior for long-term handling
Included Components
300 mm × 4.6 mm ID All‑PEEK column body (1/2‑20 threads)
2 × 2 µm PEEK frits
2 × PEEK end fittings
Use Case Positioning
4.6 mm ID / 300 mm Length
Ultra-high resolution and maximum peak capacity
Ideal for very complex mixtures and difficult separations
Best suited for method validation, regulatory work, and impurity tracing
Typical Applications
High-resolution protein and peptide separations
Nucleic acid analysis and characterization
Ion chromatography of metal-sensitive compounds
Impurity profiling and trace analysis
Advanced bioanalytical method validation
LC‑MS workflows requiring fully bioinert flow paths
⚠️ When to Use PEEK Column Hardware
Choose All‑PEEK columns when:
Analytes are sensitive to stainless steel interaction
Maximum resolution, recovery, and reproducibility are required
Working with biomolecules or coordination-sensitive compounds
Packing & Compatibility
For optimal performance:
Use with ARE‑Applied Research™ All‑PEEK slurry reservoir kits
Select frit porosity appropriate for particle size
Maintain a fully bioinert packing and operating environment
Read guidelines for packing All‑PEEK HPLC columns and achieving consistent column performance
Specifications
Hardware Type: All‑PEEK Column Set
Internal Diameter: 4.6 mm
Length: 300 mm
Thread Type: 1/2‑20
Material: Extruded PEEK (graphite‑filled)
Frits: 2 µm PEEK
Flow Path: Metal‑free (bioinert)
Surface Treatment: None (no coatings)
Reusability: Repackable
Brand: ARE‑Applied Research™
Unit: 1 Each
Resources & Ordering Options