Catalog Number - 58846-05

58846-05 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑performance, biocompatible solvent filtration device designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, high throughput, and dependable instrument protection.

This filter incorporates a “Last Drop” flat‑profile design, allowing users to extract nearly all available solvent from reservoir bottles, which is especially beneficial for long sequences, overnight runs, and high‑volume workflows.

Manufactured with a 5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, this filter provides excellent chemical compatibility, low extractables, and consistent performance across a wide range of applications.

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Positions at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents run interruption

✅ Ideal for high‑throughput labs and long analytical runs

✅ Improves solvent efficiency and workflow continuity

5 µm PTFE Element – High Capacity Filtration

• Filters particulates ≥ 5 µm

• Protects:

  • Pump seals and check valves

  • Injector systems

  • Columns and detectors

• Larger pore size provides:

  • Higher flow capacity

  • Lower flow restriction

  • Extended service life

✅ Ideal for high flow rate applications or pre-filtered solvents

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick evaluation of contamination buildup

• Supports timely replacement decisions

✅ Helps maintain consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Ensures secure, leak‑free connection

• No additional fittings required

✅ Enables fast, reliable low‑pressure system setup

Performance Advantages – Modern HPLC Operation

Compared to smaller pore filters:

• Lower flow resistance for improved throughput

• Reduced risk of flow restriction in high‑flow systems

• Maintains stable solvent delivery

• Extends filter service intervals

✅ Aligns with best practices for high‑flow HPLC systems and solvent handling

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/16")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• LC‑MS solvent management

• Pre‑filtered solvent systems

• Routine analytical laboratory workflows

• Long‑duration chromatography runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing insertion with ferrule

• Inspect regularly for particle accumulation

• Replace filter element when flow decreases