Catalog Number - 58846-07

58846-07 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑performance, biocompatible solvent filtration device engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, very high flow capacity, and critical instrument protection.

This filter features a “Last Drop” flat‑profile design, allowing nearly complete withdrawal of mobile phase from reservoir bottles—making it especially valuable for high‑flow applications, long analytical runs, and expensive solvent systems.

Constructed with a 5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, this inlet filter delivers excellent chemical compatibility, low extractables, and stable performance across demanding analytical and biocompatible workflows.

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Designed to rest at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Reduces waste and prevents pump run‑dry events

✅ Ideal for high‑flow systems, long sequences, and solvent‑intensive workflows

✅ Improves efficiency, consistency, and solvent cost control

5 µm PTFE Element – High Flow / High Capacity Filtration

• Filters particulates ≥ 5 µm

• Protects:

  • Pump seals and check valves

  • Injector components

  • HPLC columns and detectors

• Larger pore size provides:

  • Very high flow capacity

  • Minimal flow restriction

  • Extended service life

✅ Ideal for high‑flow systems or pre‑filtered solvents

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables rapid contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Ensures:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

Tripod Connector – Universal, Tool‑Free Integration

• All‑PEEK tripod tubing connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• No ferrules or nuts required

• Simple push‑fit tubing installation

✅ Enables fast setup and flexible system configuration across multiple tubing sizes

Performance Advantages – Modern HPLC Operation

Compared to finer‑pore inlet filters:

• Lower flow resistance for improved throughput

• Reduced clogging risk in high‑flow applications

• Stable solvent delivery at higher flow rates

• Longer intervals between maintenance

✅ Aligns with best practices for high‑flow chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations (1/16" and 1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• LC‑MS solvent protection

• Pre‑filtered solvent systems

• Routine analytical workflows

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure tubing is properly seated for secure connection

• Inspect filter element periodically for buildup

• Replace when flow resistance increases