HPLC Column, Hyper Similars C18, 3um, 4.0mm ID x 50mm Length, 150A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Hyper Similars C18™ is a traditional reversed-phase HPLC stationary phase designed as a high-quality alternative to established C18 methods. Part of the Cogent™ Similars product line, it is manufactured on high-purity Type-B spherical silica with a fully endcapped octadecyl (C18) bonded phase. The silica surface characteristics closely resemble those of legacy Hypersil® and Spherisorb® columns, making it an excellent choice for USP L1 methods, method transfer projects, and replacement of discontinued C18 columns while maintaining familiar retention, selectivity, and reproducibility.
62318-05P-4 is a 50 mm x 4.0 mm ID analytical column packed with 3 µm, 150Å Hyper Similars C18 particles. The short 50 mm length is optimized for rapid analyses, reduced solvent consumption, and high-throughput workflows. The 3 µm particle size provides greater efficiency and sharper peaks than comparable 5 µm columns, although higher operating backpressure should be expected. The 4.0 mm ID format is often selected for reproducing legacy methods originally developed on 4.0 mm ID columns and typically operates at approximately 0.8–1.5 mL/min on conventional HPLC systems.
This USP L1 column is ideal for hydrophobic and neutral compounds requiring strong reversed-phase retention. Typical applications include pharmaceutical analysis, long-chain fatty acid separations, quality control testing, method development, and routine analytical HPLC. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
Type-B spherical silica stationary phase
Suitable alternative for USP L1 methods
Comparable selectivity to Hypersil® and Spherisorb® C18 columns
Fast analysis with 50 mm column length
Higher efficiency with 3 µm particles
Sharper peaks and improved resolution
Excellent for hydrophobic and neutral compounds
End-capped C18 bonded phase
Typical Applications
USP L1 methods
Reversed-phase HPLC
Pharmaceutical analysis
Quality control testing
Method development
Long-chain fatty acid analysis
Fast analytical separations
Method transfer and validation
Specifications
Product Type: HPLC Column
Stationary Phase: Hyper Similars C18
USP Classification: L1
Particle Size: 3 µm
Particle Type: Type-B Spherical Silica
Bonded Phase: C18 (Octadecyl)
Endcapped: Yes
Pore Size: 150Å
Column Dimensions: 4.0 mm ID x 50 mm
Length: 50 mm
Recommended Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for reversed-phase chromatography
Short column length provides rapid analyses
3 µm particles provide higher efficiency and sharper peaks
Higher backpressure than comparable 5 µm columns
Compatible with conventional HPLC systems
Excellent alternative for many USP L1 methods
Special Order Item