HPLC Column, Hyper Similars C18, 3um, 4.0mm ID x 100mm Length, 150A. Cogent Brand. 1 EA. Special Order Item.

Additional Information:

Hyper Similars C18™ is a traditional reversed-phase HPLC stationary phase designed as a high-quality alternative to established C18 methods. Part of the Cogent™ Similars product line, it is manufactured on high-purity Type-B spherical silica with a fully endcapped octadecyl (C18) bonded phase. The silica surface characteristics closely resemble those of legacy Hypersil® and Spherisorb® columns, making it an excellent choice for USP L1 methods, method transfer projects, and replacement of discontinued C18 columns. This stationary phase delivers the strong hydrophobic retention, reproducibility, and broad applicability expected from a conventional C18 chemistry.

62318-10P-4 is a 100 mm x 4.0 mm ID analytical column packed with 3 µm, 150Å Hyper Similars C18 particles. The 100 mm length provides an excellent balance between analysis speed and chromatographic resolution, making it suitable for routine analytical methods and quality control testing. The 3 µm particle size produces higher efficiency and sharper peaks than comparable 5 µm packings while maintaining compatibility with conventional HPLC systems. The 4.0 mm ID format is often selected when reproducing legacy methods developed on 4.0 mm ID columns and typically operates at approximately 0.8–1.5 mL/min.

This USP L1 column is ideal for hydrophobic and neutral compounds requiring strong reversed-phase retention. Common applications include pharmaceutical analysis, long-chain fatty acid separations, quality control testing, method development, and routine analytical HPLC. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • Type-B spherical silica stationary phase

  • Suitable alternative for USP L1 methods

  • Comparable selectivity to Hypersil® and Spherisorb® C18 columns

  • Balanced speed and resolution with 100 mm length

  • Higher efficiency with 3 µm particles

  • Sharper peaks and improved resolution

  • Excellent for hydrophobic and neutral compounds

  • End-capped C18 bonded phase

Typical Applications

  • USP L1 methods

  • Reversed-phase HPLC

  • Pharmaceutical analysis

  • Quality control testing

  • Method development

  • Long-chain fatty acid analysis

  • Routine analytical separations

  • Method transfer and validation

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: Hyper Similars C18

  • USP Classification: L1

  • Particle Size: 3 µm

  • Particle Type: Type-B Spherical Silica

  • Bonded Phase: C18 (Octadecyl)

  • Endcapped: Yes

  • Pore Size: 150Å

  • Column Dimensions: 4.0 mm ID x 100 mm

  • Length: 100 mm

  • Recommended Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Special Order Item Information

This item is a Special Order Item manufactured specifically to customer requirements.

Important Notes

  • Designed for reversed-phase chromatography

  • 100 mm length balances speed and resolution

  • 3 µm particles provide higher efficiency and sharper peaks

  • Higher backpressure than comparable 5 µm columns

  • Compatible with conventional HPLC systems

  • Excellent alternative for many USP L1 methods

  • Special Order Item


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