HPLC Column, Hyper Similars C18, 5um, 3.0mm ID x 100mm Length, 150A. Cogent Brand. 1 EA. Special Order Item.

Additional Information:

Hyper Similars C18™ is a traditional reversed-phase HPLC stationary phase manufactured on high-purity Type-B spherical silica with a fully endcapped octadecyl (C18) bonded phase. Designed as a cost-effective alternative to legacy Hypersil® and Spherisorb® columns, it offers comparable chromatographic behavior for USP L1 methods while providing the strong hydrophobic retention, reproducibility, and broad applicability expected from a conventional C18 stationary phase.

62518-10P-3 is a 100 mm x 3.0 mm ID analytical column packed with 5 µm, 150Å Hyper Similars C18 particles. The 3.0 mm ID format reduces solvent consumption compared to standard 4.6 mm columns while maintaining good sample capacity and chromatographic performance. This column is well suited for LC-MS and solvent-saving applications, typically operating at approximately 0.4–0.6 mL/min. Due to the reduced diameter, the HPLC system must be capable of reliable low-flow operation with appropriately low-volume system components.

This USP L1 column is ideal for hydrophobic and neutral compounds requiring strong reversed-phase retention. Common applications include pharmaceutical analysis, long-chain fatty acid separations, method development, and LC-MS workflows where solvent savings and improved detector sensitivity are desired. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • Type-B spherical silica stationary phase

  • Suitable alternative for USP L1 methods

  • Comparable selectivity to Hypersil® and Spherisorb® C18 columns

  • Solvent-saving 3.0 mm ID format

  • Reliable performance with 5 µm particles

  • Strong hydrophobic retention

  • Well suited for LC-MS applications

  • End-capped C18 bonded phase

Typical Applications

  • USP L1 methods

  • Reversed-phase HPLC

  • LC-MS analysis

  • Pharmaceutical analysis

  • Long-chain fatty acid analysis

  • Method development

  • Quality control testing

  • Method transfer and validation

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: Hyper Similars C18

  • USP Classification: L1

  • Particle Size: 5 µm

  • Particle Type: Type-B Spherical Silica

  • Bonded Phase: C18 (Octadecyl)

  • Endcapped: Yes

  • Pore Size: 150Å

  • Column Dimensions: 3.0 mm ID x 100 mm

  • Length: 100 mm

  • Recommended Flow Rate: 0.4–0.6 mL/min

  • Brand: Cogent

Special Order Item Information

This item is a Special Order Item manufactured specifically to customer requirements.

Important Notes

  • Designed for reversed-phase chromatography

  • 3.0 mm ID format reduces solvent consumption

  • Requires an HPLC system capable of reliable low-flow operation

  • Lower flow rates can improve LC-MS compatibility

  • Reliable operation on conventional HPLC systems configured for reduced flow

  • Excellent alternative for many USP L1 methods

  • Special Order Item


Special Order Item. Inquire for more information.

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