Catalog Number - 67086-15P

Cogent IEX SCX is a strong cation exchange (SCX) HPLC stationary phase manufactured using high-purity silica and sulfonic acid functional groups that maintain a permanent negative charge across a wide pH range. This strong cation exchange mechanism provides reliable retention and separation of positively charged analytes, making the column suitable for ion exchange chromatography methods involving basic compounds, amines, peptides, pharmaceuticals, and other cationic species. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust cation exchange selectivity.

67086-15P is a 150 mm x 4.6 mm ID analytical column packed with 10 µm SCX particles with a 100 Å pore size. The 150 mm length provides increased resolving power for more demanding ion exchange separations while maintaining the low backpressure advantages associated with 10 µm particles. This configuration is well suited for complex samples requiring greater retention and improved separation of closely related cationic species. Typical operating flow rates are approximately 1.0–3.0 mL/min on conventional HPLC systems.

This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other ionic species. The combination of strong cation exchange functionality, high capacity, and low backpressure makes it ideal for routine analytical testing, method development, purification workflows, and quality control laboratories requiring enhanced chromatographic resolution.

Key Benefits

• Strong cation exchange (SCX) stationary phase

• Sulfonic acid functional groups

• Permanent negative surface charge

• Suitable alternative for USP L9 methods

• 10 µm particles for lower backpressure

• Supports higher flow rates

• Increased resolution from 150 mm column length

• High-purity silica support

Typical Applications

• USP L9 methods

• Ion exchange chromatography

• Basic compound analysis

• Pharmaceutical analysis

• Amine separations

• Peptide analysis

• Method development

• Quality control testing

Specifications

• Product Type: HPLC Column

• Stationary Phase: IEX SCX

• USP Classification: L9

• Chromatography Mode: Strong Cation Exchange

• Functional Group: Sulfonic Acid

• Particle Size: 10 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 150 mm

• Length: 150 mm

• Recommended Flow Rate: 1.0–3.0 mL/min

• Brand: Cogent

Important Notes

• Designed for ion exchange chromatography

• Retains positively charged analytes

• Sulfonic acid groups remain charged across a broad pH range

• Increased resolving power for complex separations

• Lower backpressure compared to smaller particle columns

• Supports higher flow rates for routine methods

• Excellent alternative for many USP L9 methods

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