HPLC Column, IEX SCX, 10um, 4.0mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent IEX SCX is a strong cation exchange (SCX) HPLC stationary phase manufactured using high-purity silica and sulfonic acid functional groups that maintain a permanent negative charge across a wide pH range. This strong cation exchange mechanism provides reliable retention and separation of positively charged analytes, making the column suitable for ion exchange chromatography methods involving basic compounds, amines, peptides, pharmaceuticals, and other cationic species. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust cation exchange selectivity.
67086-25P-4 is a 250 mm x 4.0 mm ID analytical column packed with 10 µm SCX particles with a 100 Å pore size. The extended 250 mm length provides increased theoretical plate counts and maximum resolving power for complex ion exchange separations, impurity profiling, purification studies, and challenging analytical applications requiring enhanced separation of closely related cationic compounds. The 10 µm particle size provides low backpressure and supports higher flow rates than smaller particle packings. The 4.0 mm ID format is commonly selected for legacy methods and typically operates at approximately 0.8–2.5 mL/min on conventional HPLC systems.
This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other ionic species. The combination of strong cation exchange functionality, high capacity, and extended column length makes it ideal for applications where maximum resolution and chromatographic selectivity are required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
Strong cation exchange (SCX) stationary phase
Sulfonic acid functional groups
Permanent negative surface charge
Suitable alternative for USP L9 methods
10 µm particles for lower backpressure
Supports higher flow rates
Maximum resolving power from 250 mm column length
High-purity silica support
Typical Applications
USP L9 methods
Ion exchange chromatography
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Impurity profiling
Purification studies
Specifications
Product Type: HPLC Column
Stationary Phase: IEX SCX
USP Classification: L9
Chromatography Mode: Strong Cation Exchange
Functional Group: Sulfonic Acid
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Recommended Flow Rate: 0.8–2.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for ion exchange chromatography
Retains positively charged analytes
Sulfonic acid groups remain charged across a broad pH range
Longer column length provides maximum chromatographic resolution
Lower backpressure compared to smaller particle columns
Supports higher flow rates for routine and preparative methods
Excellent alternative for many USP L9 methods
Special Order Item