Catalog Number - 67585-10P

Cogent IEX SAX is a strong anion exchange (SAX) HPLC stationary phase manufactured using high-purity silica and quaternary amine functional groups that maintain a permanent positive charge across a wide pH range. This strong anion exchange mechanism provides reliable retention and separation of negatively charged analytes, making the column suitable for ion exchange chromatography methods involving inorganic anions, organic acids, biomolecules, and other ionic compounds. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust anion exchange selectivity.

67585-10P is a 100 mm x 4.6 mm ID analytical column packed with 5 µm SAX particles with a 100 Å pore size. The 100 mm length provides an excellent balance between chromatographic resolution and analysis time, while the 5 µm particle size delivers improved efficiency, sharper peak shapes, and higher plate counts than larger particle packings. Typical operating flow rates are approximately 1.0–2.0 mL/min, making this column well suited for conventional HPLC systems and routine ion exchange applications.

This USP L9 column is particularly useful for the separation and purification of negatively charged compounds, including organic acids, inorganic anions, nucleotides, and other ionic species. The combination of strong anion exchange functionality, high efficiency, and excellent reproducibility makes it ideal for routine analytical testing, method development, quality control laboratories, and demanding ion exchange applications requiring enhanced chromatographic performance.

Key Benefits

• Strong anion exchange (SAX) stationary phase

• Quaternary amine functional groups

• Permanent positive surface charge

• Suitable alternative for USP L9 methods

• 5 µm particles for improved efficiency and resolution

• Balanced resolution and analysis time

• High chromatographic performance

• High-purity silica support

Typical Applications

• USP L9 methods

• Ion exchange chromatography

• Organic acid analysis

• Inorganic anion separations

• Biomolecule analysis

• Method development

• Purification studies

• Quality control testing

Specifications

• Product Type: HPLC Column

• Stationary Phase: IEX SAX

• USP Classification: L9

• Chromatography Mode: Strong Anion Exchange

• Functional Group: Quaternary Amine

• Particle Size: 5 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 100 mm

• Length: 100 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Designed for ion exchange chromatography

• Retains negatively charged analytes

• Quaternary amine groups remain charged across a broad pH range

• 100 mm length balances resolution and run time

• Higher efficiency than comparable 10 µm ion exchange columns

• Compatible with conventional HPLC systems

• Excellent alternative for many USP L9 methods

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