HPLC Column, IEX SCX, 5um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent IEX SCX is a strong cation exchange (SCX) HPLC stationary phase manufactured using high-purity silica and sulfonic acid functional groups that maintain a permanent negative charge across a wide pH range. This strong cation exchange mechanism provides reliable retention and separation of positively charged analytes, making the column suitable for ion exchange chromatography methods involving basic compounds, amines, peptides, pharmaceuticals, and other cationic species. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust cation exchange selectivity.
67586-05P is a 50 mm x 4.6 mm ID analytical column packed with 5 µm SCX particles with a 100 Å pore size. The short 50 mm length is optimized for rapid ion exchange separations and fast equilibration, while the 5 µm particle size provides improved chromatographic efficiency, sharper peak shapes, and greater resolving power than larger particle packings. Typical operating flow rates are approximately 1.0–2.0 mL/min, providing an excellent balance of efficiency, speed, and compatibility with conventional HPLC systems.
This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other ionic species. The combination of strong cation exchange functionality, high efficiency, and excellent reproducibility makes it ideal for routine analytical testing, method development, quality control laboratories, and demanding ion exchange applications requiring enhanced chromatographic performance.
Key Benefits
Strong cation exchange (SCX) stationary phase
Sulfonic acid functional groups
Permanent negative surface charge
Suitable alternative for USP L9 methods
5 µm particles for improved efficiency and resolution
High chromatographic performance
Fast analysis with 50 mm column length
High-purity silica support
Typical Applications
USP L9 methods
Ion exchange chromatography
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Method development
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: IEX SCX
USP Classification: L9
Chromatography Mode: Strong Cation Exchange
Functional Group: Sulfonic Acid
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Designed for ion exchange chromatography
Retains positively charged analytes
Sulfonic acid groups remain charged across a broad pH range
Short column length provides rapid analyses
Higher efficiency than comparable 10 µm ion exchange columns
Compatible with conventional HPLC systems