HPLC Column, RP C4 Butyl, 10um, 4.0mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. Classified as USP L26, this stationary phase provides moderate hydrophobic retention and is an excellent choice when compounds are retained too strongly on more hydrophobic phases such as C8 or C18. The C4 chemistry delivers reliable selectivity for hydrophobic and neutral analytes while maintaining shorter retention times and efficient chromatographic performance.
68004-25P-4 is a 250 mm x 4.0 mm ID analytical HPLC column packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The extended 250 mm column length provides maximum resolving power and increased peak capacity, making it well suited for complex separations, impurity profiling, and applications requiring enhanced chromatographic resolution. The 10 µm particle size supports higher flow rates with lower operating backpressure, while the 4.0 mm ID format is commonly selected for legacy methods and conventional HPLC systems and typically operates at approximately 0.8–1.5 mL/min.
This USP L26 column is particularly useful for hydrophobic and neutral compounds requiring less retention than a comparable C8 phase. The combination of fully endcapped C4 chemistry, high-purity silica, larger particle technology, and extended column length delivers robust chromatographic performance for method optimization, scale-up studies, and preparative method development. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
USP L26 classification
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
High-purity silica support
10 µm particles for lower backpressure
Suitable for higher flow rates
Less retention than C8 columns
Maximum resolution from 250 mm column length
Excellent for preparative method development
Typical Applications
Reversed-phase HPLC
USP L26 methods
Hydrophobic compound analysis
Neutral compound analysis
Complex sample separations
Impurity profiling
Method development
Preparative method scouting
Scale-up studies
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4 Butyl
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Recommended Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for reversed-phase chromatography
Provides less retention than comparable C8 columns
Suitable for hydrophobic and neutral compounds
Larger particle size reduces operating backpressure
Extended column length maximizes chromatographic resolution
Compatible with conventional HPLC systems
Alternative for many USP L26 methods
Special Order Item