Prep HPLC Column, RP C4, 10um, 100A. 21.2mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds that may be retained too strongly on C18 phases while providing greater retention than many C8 phases. The fully endcapped design delivers reliable chromatographic performance and reproducible purification results.
68004-P21-250 is a preparative HPLC column with dimensions of 21.2 mm ID x 250 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The large internal diameter is designed for high sample loading and fraction collection, while the 250 mm length provides maximum resolving power and peak capacity for demanding purification applications. Typical flow rates are approximately 15–40 mL/min, depending on mobile phase composition, analyte properties, and system capabilities.
This column is intended for preparative HPLC purification where target compounds are isolated and collected for further research, development, formulation, or production. The extended column length is particularly beneficial when separating closely related compounds, optimizing purification methods, or scaling laboratory processes to larger sample loads. A specialized preparative HPLC system capable of higher flow rates, larger injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for preparative HPLC purification
High sample loading capacity
10 µm particles for lower operating backpressure
Suitable for higher flow rates
Less retention than C18 columns
Maximum resolving power with 250 mm column length
Excellent for compound isolation and purification
Typical Applications
Preparative HPLC purification
Small molecule isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process development
Scale-up studies
Pilot-scale purification
Fraction collection
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 21.2 mm ID x 250 mm
Length: 250 mm
Typical Flow Rate: 15–40 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification rather than routine analytical HPLC
Used for isolation and collection of purified compounds
Offers substantially higher sample loading capacity than analytical columns
Requires a preparative HPLC system capable of higher flow rates and fraction collection
Provides less retention than C18 phases and greater retention than many C8 phases
Ideal for process development, scale-up studies, and production-support purification
Special Order Item