HPLC Column, RP C8 Octyl, Wide Pore, 10um, 4.6mm ID x 50mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C8 Octyl Wide Pore is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The 300 Å pore structure is specifically designed to improve accessibility for larger molecules while maintaining the moderate hydrophobicity associated with C8 chemistry. This stationary phase is well suited as an alternative for USP methods that specify L7 column classifications, particularly when larger analytes require enhanced pore accessibility and efficient mass transfer.
68008-05P-3M is an analytical HPLC column with dimensions of 4.6 mm ID x 50 mm length, packed with 10 µm RP C8 Octyl Wide Pore particles featuring a 300 Å pore size. The short 50 mm length is ideal for rapid screening, method development, and high-throughput analyses where fast run times are important. The 10 µm particle size supports higher flow rates with lower operating backpressure, making it a practical choice for routine analytical laboratories.
This column is well suited for analysis of large hydrophobic or neutral compounds, including proteins, peptides, long-chain fatty acids, and other high-molecular-weight analytes. The wide pore architecture improves analyte accessibility while the moderate retention characteristics of the C8 phase can provide faster elution than C18 columns. The short column format also makes it an effective scouting column for preparative method development prior to scale-up.
Key Benefits
RP C8 Octyl Wide Pore stationary phase
300 Å pore size optimized for larger molecules
Fully double endcapped chemistry
Traditional octyl (C8) bonded phase
Suitable alternative for USP L7 methods
Lower retention than C18 columns
10 µm particles for lower operating backpressure
Short column for rapid analyses
Effective scouting column for preparative methods
High-purity silica support
Typical Applications
USP L7 methods
Protein analysis
Peptide analysis
Long-chain fatty acid analysis
Large molecule separations
Method development
Method scouting
High-throughput testing
Pharmaceutical analysis
Routine HPLC separations
Specifications
Product Type: Analytical HPLC Column
Stationary Phase: RP C8 Octyl Wide Pore
Chromatography Mode: Reversed Phase
USP Classification: L7
Bonded Phase: Octyl (C8)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 300 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Suitable as an alternative for USP L7 methods
Designed for larger molecules requiring wide pore accessibility
Provides less retention than C18 stationary phases
Commonly used for protein, peptide, and long-chain fatty acid separations
Ideal for fast analytical methods and preparative method scouting