HPLC Column, RP C8 Octyl, Wide Pore, 10um, 4.0mm ID x 100mm Length, 300A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C8 Octyl Wide Pore is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The 300 Å pore structure is specifically designed to improve accessibility for larger molecules while maintaining the moderate hydrophobicity associated with C8 chemistry. This stationary phase is well suited as an alternative for USP methods that specify L7 column classifications, particularly when larger analytes require enhanced pore accessibility and efficient mass transfer.

68008-10P-4-3M is an analytical HPLC column with dimensions of 4.0 mm ID x 100 mm length, packed with 10 µm RP C8 Octyl Wide Pore particles featuring a 300 Å pore size. The 100 mm length provides a balance between analysis speed and chromatographic resolution, making it suitable for routine analytical methods, method development, and quality control applications. The 10 µm particle size provides lower operating backpressure while supporting higher flow rates than smaller particle columns.

This column is well suited for analysis of large hydrophobic or neutral compounds, including proteins, peptides, long-chain fatty acids, and other high-molecular-weight analytes. The wide pore architecture improves analyte accessibility while the moderate retention characteristics of the C8 phase can provide faster elution than C18 columns. Its balanced selectivity and robust performance make it a practical choice for USP L7 methods, biotechnology research, pharmaceutical analysis, and routine laboratory testing. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • RP C8 Octyl Wide Pore stationary phase

  • 300 Å pore size optimized for larger molecules

  • Fully double endcapped chemistry

  • Traditional octyl (C8) bonded phase

  • Suitable alternative for USP L7 methods

  • Lower retention than C18 columns

  • 10 µm particles for lower operating backpressure

  • Balanced speed and resolution with 100 mm length

  • High-purity silica support

  • Robust analytical performance

Typical Applications

  • USP L7 methods

  • Protein analysis

  • Peptide analysis

  • Long-chain fatty acid analysis

  • Large molecule separations

  • Method development

  • Pharmaceutical analysis

  • Quality control testing

  • Biotechnology research

  • Reversed-phase HPLC separations

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: RP C8 Octyl Wide Pore

  • Chromatography Mode: Reversed Phase

  • USP Classification: L7

  • Bonded Phase: Octyl (C8)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 300 Å

  • Column Dimensions: 4.0 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 0.8–1.5 mL/min

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable as an alternative for USP L7 methods

  • Designed for larger molecules requiring wide pore accessibility

  • Provides less retention than C18 stationary phases

  • Commonly used for protein, peptide, and long-chain fatty acid separations

  • Offers a balance of speed and resolving power

  • Compatible with conventional HPLC systems

  • Special Order Item


 

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