HPLC Column, RP C8 Octyl, Wide Pore, 10um, 4.6mm ID x 150mm Length, 300A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C8 Octyl Wide Pore is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The 300 Å pore structure is specifically designed to improve accessibility for larger molecules while maintaining the moderate hydrophobicity associated with C8 chemistry. This stationary phase is well suited as an alternative for USP methods that specify L7 column classifications, particularly when larger analytes require enhanced pore accessibility and efficient mass transfer.

68008-15P-3M is an analytical HPLC column with dimensions of 4.6 mm ID x 150 mm length, packed with 10 µm RP C8 Octyl Wide Pore particles featuring a 300 Å pore size. The 150 mm length provides increased resolving power compared to shorter columns, making it well suited for methods requiring improved separation of closely related compounds. The 10 µm particle size provides lower operating backpressure while supporting robust performance and reliable method transfer.

This column is well suited for analysis of large hydrophobic or neutral compounds, including proteins, peptides, long-chain fatty acids, and other high-molecular-weight analytes. The wide pore architecture improves analyte accessibility while the moderate retention characteristics of the C8 phase can provide faster elution than C18 columns. The additional column length provides enhanced chromatographic efficiency, making it a valuable choice for biotechnology research, pharmaceutical analysis, quality control testing, and USP L7 methods.

Key Benefits

  • RP C8 Octyl Wide Pore stationary phase

  • 300 Å pore size optimized for larger molecules

  • Fully double endcapped chemistry

  • Traditional octyl (C8) bonded phase

  • Suitable alternative for USP L7 methods

  • Lower retention than C18 columns

  • 10 µm particles for lower operating backpressure

  • Enhanced resolution with 150 mm length

  • High-purity silica support

  • Robust analytical performance

Typical Applications

  • USP L7 methods

  • Protein analysis

  • Peptide analysis

  • Long-chain fatty acid analysis

  • Large molecule separations

  • Method development

  • Pharmaceutical analysis

  • Quality control testing

  • Biotechnology research

  • Reversed-phase HPLC separations

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: RP C8 Octyl Wide Pore

  • Chromatography Mode: Reversed Phase

  • USP Classification: L7

  • Bonded Phase: Octyl (C8)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 300 Å

  • Column Dimensions: 4.6 mm ID x 150 mm

  • Length: 150 mm

  • Typical Flow Rate: 1.0–2.0 mL/min

  • Brand: Cogent

Important Notes

  • Suitable as an alternative for USP L7 methods

  • Designed for larger molecules requiring wide pore accessibility

  • Provides less retention than C18 stationary phases

  • Commonly used for protein, peptide, and long-chain fatty acid separations

  • Additional column length provides greater resolving power than shorter formats

  • Compatible with conventional HPLC systems


 

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