Prep HPLC Column, RP C18, 10um, 100A. 30mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68018‑P30‑100 Cogent RP C18 Preparative HPLC Column is designed for production‑scale purification and preparative method development, utilizing 10 µm particles and fully double end‑capped C18 bonding to deliver robust performance, extremely high loading capacity, and durable chromatographic operation.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Consistent and reproducible purification performance
This column is ideal as a USP L1 alternate and as a refinement platform for scaling purification methods to full production workflows.
100 mm Length – Increased Resolution for Production Development
Higher resolving power than 50 mm scouting columns
Improved separation of closely related compounds
Increased peak capacity for preparative purification workflows
Ideal for refining methods prior to longer columns or production‑scale runs
This configuration is selected when additional resolution is required beyond initial production‑scale scouting.
30 mm ID – Maximum Production‑Scale Loading
Provides extremely high sample loading capacity
Designed for large‑scale purification and manufacturing workflows
Supports very high‑flow preparative chromatography systems
Typical Flow Rate Range
~20–60 mL/min (system dependent)
Optimize based on instrument capability and production requirements
✅ Designed for production‑scale HPLC systems with high flow rates and large injection volumes
Flow Rate & System Considerations (30 mm ID, 10 µm)
Requires systems capable of:
Very high flow rates
Large injection volumes
Compatible with:
Production preparative pumps
Large‑volume injection systems
High‑capacity fraction collection systems
⚠️ Not intended for analytical or semi‑prep HPLC systems
Why Choose RP C18 (10 µm, Production Scale)
Method Development to Production
Ideal for developing and refining purification methods prior to full‑scale manufacturing
Enables efficient scale‑up to longer columns and continuous processes
Supports consistent analytical → semi‑prep → prep → production workflows
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids
Provides greater retention than C8 phases
USP Method Compatibility
Suitable for USP L1 methods
Reliable for validated and regulated environments
Supports method transfer across all HPLC scales
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Enhances performance for challenging analytes
High Purity Silica
Consistent chromatographic performance
Reduced variability across runs and batches
Durable & Cost‑Efficient
Long column lifetime
Designed for high‑load production workflows
Reduced downtime and maintenance frequency
Typical Applications
Production‑scale purification
Preparative method development
Hydrophobic and neutral compound separations
Pharmaceutical manufacturing
Process scale‑up workflows
USP L1 reversed‑phase methods
Important Usage Notes
Designed for 30 mm production‑scale HPLC systems
Requires very high‑flow capability and large sample loading volumes
Ideal for method refinement prior to full production runs
Choose when robustness and loading capacity are prioritized over efficiency
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable