Process HPLC Column, RP C18, 10um, 100A. 50mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68018‑P50‑150 Cogent RP C18 Process HPLC Column is engineered for high‑resolution industrial purification and process chromatography development, utilizing 10 µm particles and fully double end‑capped C18 bonding to deliver exceptional durability, extremely high loading capacity, and consistent chromatographic performance in manufacturing environments.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Reproducible performance across large‑volume and continuous purification workflows
This column functions as a USP L1 alternate and as a high‑performance platform for scaling purification processes into full industrial production.
150 mm Length – Maximum Resolution for Process Optimization
Higher resolving power than 50 mm and 100 mm process columns
Maximizes peak capacity for complex mixtures
Ideal for closely related compounds and difficult separations
Preferred for final method refinement before full‑scale manufacturing
Longer run times compared to shorter column formats
This configuration is selected when maximum separation performance is required prior to production deployment or continuous processing.
50 mm ID – Maximum Industrial‑Scale Loading
Provides extremely high sample loading capacity (highest tier in the column hierarchy)
Designed for industrial purification, batch processing, and manufacturing workflows
Supports ultra‑high‑flow chromatography systems
Typical Flow Rate Range
~50–150 mL/min (system dependent)
Optimize based on process requirements and system capability
✅ Designed for process HPLC systems capable of ultra‑high flow rates and very large injection volumes
Flow Rate & System Considerations (50 mm ID, 10 µm)
Requires systems capable of:
Ultra‑high flow rates
Very large injection volumes
Compatible with:
Process chromatography systems
Industrial pumps and injection platforms
Large‑volume fraction collection or continuous processing systems
⚠️ Not suitable for analytical, semi‑prep, or standard preparative HPLC systems
Why Choose RP C18 (10 µm, Process Scale)
Maximum Resolution for Industrial Workflows
Ideal for final purification and process optimization of complex mixtures
Maximizes separation efficiency and product purity
Enables high‑purity compound manufacturing at scale
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Effective for lipids and long‑chain fatty acids
Provides greater retention than C8 phases
Method Development to Full Production
Enables efficient scale‑up from development to industrial manufacturing
Maintains consistency across analytical → semi‑prep → prep → production → process workflows
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Enhances robustness in high‑load industrial environments
High Purity Silica
Consistent chromatographic performance
Reduced variability across large‑scale production runs
Durable & Cost‑Efficient
Long column lifetime
Designed for continuous, high‑throughput process workflows
Reduces downtime and operational costs
Typical Applications
Industrial‑scale purification
High‑purity compound isolation
Complex mixture separations
Pharmaceutical manufacturing
Process development and optimization
USP L1 reversed‑phase methods
Important Usage Notes
Designed for 50 mm ID process‑scale HPLC systems
Requires ultra‑high‑flow capability and very large sample loading volumes
Ideal for maximum‑resolution purification prior to full production runs
Optimize for resolution vs throughput based on manufacturing goals
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable