HPLC Column, RP PFP, 10um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
68022-05P Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for targeted separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.
The column enables multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it especially effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.
With a 10 µm particle size, this column provides very low backpressure compared to smaller particle sizes, allowing higher flow rates and improved system compatibility, particularly in methods where pressure limitations are a concern.
50 mm Length – Fast Screening and High Throughput
The 50 mm length is optimized for rapid separations and high‑throughput workflows.
Very fast run times for screening applications
Reduced solvent consumption
Ideal for early-stage method development
✅ Recommended for fast analytical workflows and high‑flow operation
Flow Rate & System Requirements (4.6 mm ID, 10 µm)
⚠️ Fully compatible with standard analytical HPLC systems and ideal for low-pressure operation
Typical flow rate range: ~1.0 – 2.5 mL/min
Very low backpressure vs 5 µm and 3 µm columns
Supports higher flow rates for faster analyses
Suitable for UV and standard detectors
✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) Columns for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole interactions and hydrogen bonding
Increased flexibility for method optimization
100 Å Pore Structure
Suitable for small to moderately sized molecules
Broad applicability across analytical methods
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
Low Backpressure (10 µm Particles)
Ideal for high flow rate methods
Reduced strain on HPLC systems
High Purity Silica
Consistent chromatographic performance
Reliable reproducibility
Typical Applications
Fast screening and high‑throughput analysis
Halogenated compound separations
Aromatic compound analysis
Method development and optimization
USP L43 methods
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.6 mm ID)
Very low backpressure compared to smaller particle columns
Use 0.2 µm filtration prior to injection