CUSTOM ITEM: HPLC Column, RP PFP, 10um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
68022-05P-4 Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for targeted separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.
The column enables multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it particularly effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.
With a 10 µm particle size, this column provides very low backpressure, making it ideal for higher flow rates, method scouting, and applications where system pressure limitations are a concern.
50 mm Length – Fast Screening and Method Development
The 50 mm length is optimized for rapid separations and high‑throughput screening.
Very fast run times for efficient throughput
Reduced solvent consumption
Ideal for early-stage method development and scouting
✅ Recommended for rapid screening and higher flow applications
Flow Rate & System Requirements (4.0 mm ID, 10 µm)
⚠️ Designed for low backpressure operation and high flow capability
Typical flow rate range: ~1.0 – 2.0 mL/min
Significantly lower backpressure vs 5 µm and 3 µm columns
Allows use on systems with pressure limitations
Compatible with standard analytical detectors
✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) Columns for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility for method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Broad applicability across analytical workflows
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
Low Backpressure (10 µm Particles)
Ideal for high flow rate methods
Reduced system strain and improved method robustness
High Purity Silica
Consistent chromatographic performance
Reliable reproducibility
Typical Applications
Fast screening and method development
Halogenated compound analysis
Aromatic compound separations
Scale-up method scouting
USP L43 methods
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.0 mm ID)
Very low backpressure compared to smaller particles
Use 0.2 µm filtration prior to injection
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable