HPLC Column, RP PFP, 10um, 4.6mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
68022-10P Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for a wide range of separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.
The column enables multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it highly effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.
With a 10 µm particle size, this column provides very low backpressure compared to smaller particle columns, allowing higher flow rates and excellent system compatibility, particularly for systems with pressure limitations.
100 mm Length – Balanced Resolution with High Flow Capability
The 100 mm length delivers a balance between resolution and speed while supporting higher flow operation.
Improved resolution compared to 50 mm columns
Shorter run times than longer column formats
Suitable for moderate complexity separations
✅ Recommended for high‑flow analytical workflows and method development
Flow Rate & System Requirements (4.6 mm ID, 10 µm)
⚠️ Designed for high flow and low-pressure operation
Typical flow rate range: ~1.0 – 2.5 mL/min
Very low backpressure vs 5 µm and 3 µm columns
Ideal for systems with pressure limitations
Compatible with UV and standard analytical detectors
✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) Columns for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole interactions and hydrogen bonding
Greater flexibility in method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Broad applicability across analytical methods
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
Low Backpressure (10 µm Particles)
Enables high flow rate operation
Reduces strain on HPLC systems
High Purity Silica
Reproducible chromatographic performance
Long column lifetime
Typical Applications
High‑flow analytical methods
Halogenated compound analysis
Aromatic compound separations
Method development and optimization
USP L43 methods
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.6 mm ID)
Very low backpressure compared to smaller particle sizes
Use 0.2 µm filtration prior to injection