CUSTOM ITEM: HPLC Column, RP PFP, 10um, 4.0mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
68022-10P-4 Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for challenging separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.
The column provides multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it highly effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.
With a 10 µm particle size, this column offers very low backpressure compared to smaller particle columns, enabling higher flow rates and improved compatibility with systems that have pressure limitations.
100 mm Length – Balanced Performance with High Flow Capability
The 100 mm length provides a balance between resolution and run time while maintaining the advantages of low backpressure operation.
Improved resolution compared to 50 mm columns
Faster run times than longer column formats
Suitable for moderate complexity separations
✅ Recommended for method development, scale-up scouting, and high-flow analytical workflows
Flow Rate & System Requirements (4.0 mm ID, 10 µm)
⚠️ Designed for high flow and low-pressure operation
Typical flow rate range: ~1.0 – 2.0 mL/min
Very low backpressure vs 5 µm and 3 µm columns
Ideal for systems with pressure limitations
Compatible with standard analytical detectors
✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) Columns for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole interactions and hydrogen bonding
Greater flexibility in method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Broad applicability across analytical methods
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
Low Backpressure (10 µm Particles)
Supports high flow rate methods
Reduces system strain
High Purity Silica
Consistent chromatographic performance
Reliable reproducibility
Typical Applications
High‑flow analytical methods
Method development and scale‑up scouting
Halogenated compound analysis
Aromatic compound separations
USP L43 methods
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.0 mm ID)
Very low backpressure compared to smaller particle sizes
Use 0.2 µm filtration prior to injection
Custom Order Item: This column is manufactured to order and cannot be canceled or returned once the order is placed
Availability: Custom order – inquire for more information and lead time
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable