Catalog Number - 68022-15P-4

68022-15P-4 Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for complex analytical separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.

The column provides multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it highly effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.

With a 10 µm particle size, this column provides very low backpressure compared to smaller particle columns, allowing higher flow rates and improved compatibility with systems that have pressure limitations while maintaining reliable chromatographic performance.

150 mm Length – Enhanced Resolution with High Flow Capability

The 150 mm length delivers improved resolving power over shorter columns while maintaining the benefits of low backpressure.

• Higher resolution than 50 mm and 100 mm columns

• Improved separation of closely related compounds

• Increased peak capacity for moderately complex samples

✅ Recommended for analytical workflows requiring improved separation with higher flow capability

Flow Rate & System Requirements (4.0 mm ID, 10 µm)

⚠️ Designed for low-pressure, higher flow operation

• Typical flow rate range: ~0.8 – 1.8 mL/min

• Very low backpressure compared to 5 µm and 3 µm columns

• Supports higher flow rates without exceeding system limits

• Compatible with UV and standard analytical detectors

✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection

Why Choose PFP (F5) Columns for Selective Separations

Enhanced Retention for Halogenated Compounds

• Strong interaction with fluorinated and halogenated analytes

• Improved selectivity compared to C18 columns

Multiple Interaction Mechanisms

• π‑π interactions for aromatic compounds

• Dipole interactions and hydrogen bonding

• Greater flexibility for method development

100 Å Pore Structure

• Suitable for small to moderately sized molecules

• Broad applicability across analytical workflows

Cogent RP PFP™ Column Advantages

Fully End‑Capped Surface

• Minimizes silanol activity

• Improves peak symmetry

Low Backpressure (10 µm Particles)

• Ideal for high flow rate methods

• Reduced system strain and increased robustness

High Purity Silica

• Consistent chromatographic performance

• Reliable reproducibility

Typical Applications

• High‑flow analytical methods

• Halogenated compound analysis

• Aromatic compound separations

• Method development and scale‑up scouting

• USP L43 methods

Important Usage Notes

• Packed and shipped in reversed‑phase solvents

• Designed for standard analytical HPLC systems (4.0 mm ID)

• Very low backpressure compared to smaller particle columns

• Use 0.2 µm filtration prior to injection

• Custom Order Item: This column is manufactured to order and cannot be canceled or returned once the order is placed

• Availability: Custom order – inquire for details and lead time