Prep Guard Column Cartridge, RP PFP, 10um, 100A. 21.2mm ID x 10mm Length. Cogent Brand. 1 EA.
Additional Info:
68022-P21-PG1 Cogent RP PFP™ Guard Column Cartridge is designed to protect preparative HPLC columns from particulates and strongly retained contaminants that can degrade column performance and reduce lifespan. Packed with 10 µm Cogent RP PFP™ material, this guard cartridge provides matched selectivity for RP PFP preparative columns.
The column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This ensures consistent chromatographic behavior and maintains method integrity during preparative separations.
Constructed in a stainless steel tube with stainless steel frits, this guard cartridge is designed for durability and reliability under high‑flow preparative conditions.
21.2 mm ID × 10 mm Length – Preparative Column Protection
This guard cartridge is optimized for use with 21.2 mm ID preparative columns, providing effective protection with minimal impact on system pressure.
Protects against particulates and matrix contamination
Extends preparative column lifetime
Preserves RP PFP selectivity during purification
✅ Recommended for all preparative workflows using 21.2 mm ID RP PFP columns
Flow Rate & System Requirements (21.2 mm ID, 10 µm)
⚠️ Requires preparative HPLC system capability
Typical flow rate range: ~10 – 30 mL/min
Very low backpressure compared to smaller particle sizes
Designed for high-flow preparative operation
Compatible with fraction collection systems and preparative detectors
✅ Important: A specialized preparative HPLC system is required for columns of this size
✅ Required Hardware: Use with a 21.2 mm ID preparative guard column holder (see Guard Column Holder product page for compatibility and specifications)
Why Use RP PFP Guard Columns
Column Protection
Prevents contamination of high-value preparative columns
Reduces irreversible adsorption and fouling
Maintains Selectivity
Matches RP PFP column chemistry
Ensures consistent purification results
Improves Operational Efficiency
Reduces downtime and replacement frequency
Extends column life
Cogent RP PFP™ Guard Cartridge Advantages
Matched Chemistry
Same selectivity as RP PFP preparative columns
Durable Construction
Stainless steel housing and frits for high-flow operation
Low Backpressure (10 µm Particles)
Ideal for large-scale, high-flow applications
Typical Applications
Preparative HPLC purification
Large-scale compound isolation
Halogenated compound separations
Aromatic compound purification
Pharmaceutical scale‑up workflows
Important Usage Notes
Designed for use with 21.2 mm ID preparative guard column holders
Packed and shipped in reversed‑phase solvents
Requires preparative HPLC system capability
Replace guard cartridges regularly to maintain system performance
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable