Prep HPLC Column, RP PFP, 10um, 100A. 30mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Info:
68022-P30-50 Cogent RP PFP™ Prep HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for preparative and production‑scale separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica.
The column provides multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it especially effective for halogenated, aromatic, and polar analytes. These interactions improve selectivity compared to conventional reversed‑phase columns, enabling efficient purification of structurally similar compounds.
With a 10 µm particle size, this column offers very low backpressure, allowing significantly higher flow rates and improved compatibility with high‑capacity preparative HPLC systems.
50 mm Length – Fast Large‑Scale Purification
The 50 mm length is optimized for speed and throughput in large‑scale purification workflows.
Very fast purification cycles and short run times
Reduced solvent usage compared to longer columns
Ideal for method scouting and early-stage scale‑up
✅ Recommended for high‑throughput purification and rapid preparative screening
Flow Rate & System Requirements (30 mm ID, 10 µm)
⚠️ Requires preparative or process‑scale HPLC system capability
Typical flow rate range: ~20 – 60 mL/min
Extremely low backpressure vs 5 µm and 3 µm columns
Designed for very high‑flow preparative operation
Compatible with large‑scale fraction collection systems
✅ Important: A specialized preparative HPLC system is required for columns of this size
✅ Best Practice: Use appropriate sample filtration and a matched RP PFP guard column cartridge to protect the column and maintain performance
Why Choose PFP (F5) Columns for Preparative Work
Enhanced Selectivity for Complex Mixtures
Strong interaction with halogenated and fluorinated compounds
Improved selectivity vs traditional C18 phases
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole interactions and hydrogen bonding
Greater flexibility for purification method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Consistent performance from analytical to large‑scale preparative systems
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry and compound recovery
Ultra‑Low Backpressure (10 µm Particles)
Enables very high flow rate operation
Reduces strain on large-scale HPLC systems
High Purity Silica
Reliable and reproducible chromatographic performance
Consistent purification results at scale
Typical Applications
Large‑scale preparative HPLC purification
Process-scale compound isolation
Halogenated compound purification
Aromatic compound separations
Pharmaceutical production and scale‑up
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Requires preparative or process‑scale HPLC system capability
Designed for high‑flow operation (30 mm ID columns)
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable