Prep Guard Column Cartridge, RP PFP, 10um, 100A. 30mm ID x 10mm Length. Cogent Brand. 1 EA.

Additional Info:

68022-P30-PG1 Cogent RP PFP™ Guard Column Cartridge is designed to protect large‑scale preparative HPLC columns from particulates and strongly retained contaminants that can degrade column performance and shorten operational life. Packed with 10 µm Cogent RP PFP™ material, this guard cartridge provides matched selectivity with minimal added backpressure.

The packing material is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This ensures consistent chromatography and preserves separation integrity during high‑flow preparative operations.

Constructed in a durable stainless steel tube with stainless steel frits, this cartridge is engineered to withstand the demanding pressures and flow rates of large‑scale purification systems.

30 mm ID × 10 mm Length – Large‑Scale Prep Column Protection

Designed specifically for 30 mm ID preparative columns, this guard cartridge minimizes contamination while maintaining system efficiency.

  • Protects against particulates and sample matrix fouling

  • Extends lifespan of high-value prep columns

  • Preserves RP PFP selectivity in purification workflows

✅ Recommended for large‑scale preparative workflows using 30 mm ID RP PFP columns

Flow Rate & System Requirements (30 mm ID, 10 µm)

⚠️ Requires preparative or process-scale HPLC system capability

  • Typical flow rate range: ~20 – 60 mL/min

  • Extremely low backpressure due to 10 µm particle size

  • Designed for very high‑flow preparative operation

  • Compatible with large‑scale fraction collection systems

✅ Important: A specialized preparative HPLC system is required for columns of this size

✅ Required Hardware: Use with a 30 mm ID preparative guard column holder (see Guard Column Holder product page for compatibility and specifications)

Why Use RP PFP Guard Columns

Column Protection

  • Prevents contamination and particulate buildup

  • Reduces irreversible adsorption on prep columns

Maintains Selectivity

  • Matches RP PFP column chemistry

  • Ensures consistent purification performance

Improves Operational Efficiency

  • Reduces downtime and maintenance frequency

  • Extends column lifetime in high-throughput environments

Cogent RP PFP™ Guard Cartridge Advantages

Matched Chemistry

  • Same selectivity as RP PFP preparative columns

Durable Construction

  • Stainless steel housing and frits for high-flow use

Ultra-Low Backpressure (10 µm Particles)

  • Ideal for large-scale and process HPLC

Typical Applications

  • Large‑scale preparative HPLC purification

  • Process-scale compound isolation

  • Halogenated compound separations

  • Aromatic compound purification

  • Pharmaceutical production and scale‑up

Important Usage Notes

  • Designed for use with 30 mm ID preparative guard column holders

  • Packed and shipped in reversed‑phase solvents

  • Requires preparative/system-scale HPLC capability

  • Replace guard cartridges regularly to maintain system performance

Made‑to‑Order Columns & Pricing Information

This is a custom, made‑to‑order column.

  • Columns are manufactured specifically to order

  • Orders cannot be canceled once placed

  • Custom columns are non‑returnable

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