Process HPLC Column, RP PFP, 10um, 100A. 50mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
68022-P50-150 Cogent RP PFP™ Process HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for process‑scale and production‑level purification. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica.
The column provides multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it highly effective for halogenated, aromatic, and polar analytes. These mechanisms improve separation of structurally similar compounds and enable high purity in large‑scale workflows.
With a 10 µm particle size, this column offers extremely low backpressure, supporting very high flow rates and improving compatibility with large‑diameter process HPLC systems.
150 mm Length – Enhanced Resolution at Process Scale
The 150 mm length delivers increased resolving power compared to shorter columns while maintaining high throughput.
Higher resolution than 50 mm and 100 mm process columns
Improved separation of closely related compounds
Increased peak capacity for complex mixtures
✅ Recommended for production workflows requiring improved separation performance
Flow Rate & System Requirements (50 mm ID, 10 µm)
⚠️ Requires process‑scale or pilot‑scale HPLC system capability
Typical flow rate range: ~40 – 150 mL/min
Extremely low backpressure vs smaller particle sizes
Designed for ultra high‑flow operation
Compatible with industrial fraction collection systems
✅ Important: A specialized process‑scale HPLC system is required for columns of this size
✅ Best Practice: Use appropriate sample filtration and a matched RP PFP guard column cartridge to protect the column and maintain long‑term performance
Why Choose PFP (F5) Columns for Process‑Scale Work
Enhanced Selectivity for Complex Mixtures
Strong interaction with halogenated and fluorinated analytes
Improved selectivity vs traditional C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility for purification method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Consistent performance from analytical to full process scale
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry and recovery
Ultra‑Low Backpressure (10 µm Particles)
Enables very high flow rate operation
Reduces system strain in large-scale HPLC systems
High Purity Silica
Reliable and reproducible chromatographic performance
Consistent purification results in production environments
Typical Applications
Process‑scale HPLC purification
Pilot‑scale and production compound isolation
Halogenated compound purification
Aromatic compound separations
Pharmaceutical manufacturing and scale‑up
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Requires process‑scale HPLC system capability
Designed for ultra high‑flow operation (50 mm ID columns)
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable