Semi Prep HPLC Column, RP PFP, 10um, 100A. 10mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
68022-SP150 Cogent RP PFP™ Semi Prep HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering reliable performance and enhanced selectivity for purification and scale‑up applications. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica.
The column provides multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it especially effective for halogenated, aromatic, and polar analytes. These mechanisms enable improved separation of structurally similar compounds during preparative workflows.
With a 10 µm particle size, this column offers very low backpressure compared to smaller particle columns, allowing higher flow rates and improving system compatibility for preparative HPLC systems where throughput and pressure limitations are key considerations.
150 mm Length – Enhanced Resolution for Purification
The 150 mm length provides increased resolving power compared to shorter semi‑prep columns, making it ideal for more complex separations.
Higher resolution than 50 mm and 100 mm columns
Improved separation of closely related compounds
Increased peak capacity for moderately complex samples
✅ Recommended for purification workflows requiring improved separation performance
Flow Rate & System Requirements (10 mm ID, 10 µm)
⚠️ Requires semi‑preparative or preparative HPLC system capability
Typical flow rate range: ~3.0 – 6.0 mL/min
Very low backpressure compared to 5 µm and 3 µm columns
Designed for high‑flow preparative operation
Compatible with fraction collectors and preparative detectors
✅ Important: A specialized HPLC system capable of semi‑prep or preparative flow rates is required
✅ Best Practice: Use sample filtration and/or guard column protection to maintain column performance and extend column life
Why Choose PFP (F5) Columns for Semi‑Prep Work
Enhanced Selectivity for Complex Samples
Strong interaction with halogenated and fluorinated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility in purification method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Consistent selectivity from analytical to preparative scale
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry and compound recovery
Low Backpressure (10 µm Particles)
Enables high flow rate operation
Reduces strain on preparative systems
High Purity Silica
Consistent chromatographic performance
Reliable and reproducible results
Typical Applications
Semi‑prep purification workflows
Method development and scale‑up
Halogenated compound purification
Aromatic compound isolation
Pharmaceutical development and preparative analysis
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Requires semi‑prep or preparative HPLC system
Designed for high‑flow operation (10 mm ID columns)
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable