HPLC Column, RP Cyano, 10um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA. CUSTOM ORDER.
Additional Information:
Cogent RP Cyano is a versatile reversed-phase stationary phase designed for HPLC methods requiring lower hydrophobic retention, rapid equilibration, and selectivity different from traditional C18 columns. Manufactured using high-purity silica with a cyanopropyl (CN) bonded phase, it is widely used as an alternative for USP L10 methods and provides excellent performance for polar and neutral compounds. The unique cyano functionality can improve method flexibility during column screening and method development.
68034-05P-4 is an analytical HPLC column packed with 10 µm RP Cyano particles featuring a 100 Å pore size in a 4.0 mm ID x 50 mm format. The short column length is ideal for rapid analyses, fast method development, and preparative method scouting. The 10 µm particle size supports lower operating backpressure and allows higher flow rates when appropriate. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, analyte characteristics, and instrument configuration.
This column is commonly used for analysis of polar and neutral compounds where reduced retention and fast equilibration are beneficial. It is also frequently selected for USP L10 methods and as a scouting column for preparative method development.
Key Benefits
RP Cyano stationary phase
USP L10 column equivalent chemistry
Cyanopropyl bonded phase
High-purity silica support
Alternative selectivity to C18 columns
Faster equilibration than many traditional reversed-phase columns
Reduced hydrophobic retention
Suitable for polar and neutral compounds
Lower operating backpressure with 10 µm particles
Useful for method development and preparative scouting
Typical Applications
USP L10 methods
Method development
Preparative method scouting
Polar compound analysis
Neutral compound analysis
Pharmaceutical analysis
Quality control testing
Routine HPLC analysis
Fast separations
Alternative selectivity screening
Specifications
Product Type: HPLC Column
Stationary Phase: RP Cyano
USP Classification: L10
Chromatography Mode: Reversed Phase
Bonded Phase: Cyanopropyl (CN)
Endcapping: Not Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Packed and shipped in reversed-phase solvents
Commonly used as an alternative selectivity choice to traditional C18 columns
Short column length is ideal for rapid analyses and method scouting
Frequently selected for USP L10 methods
Suitable for transferring promising methods to larger-scale columns