HPLC Column, RP Cyano, Wide Pore, 10um, 4.0mm ID x 100mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Cyano Wide Pore is a versatile reversed-phase stationary phase designed for HPLC methods requiring lower hydrophobic retention, rapid equilibration, and alternative selectivity compared to traditional C18 columns. Manufactured using high-purity silica with a cyanopropyl (CN) bonded phase, it provides balanced retention for polar and moderately hydrophobic compounds while serving as an effective USP L10 alternative. The 300 Å wide pore structure improves accessibility for larger molecules, making it especially well suited for biomolecules and other high molecular weight analytes.
68034-10P-4-3M is an analytical HPLC column packed with 10 µm RP Cyano Wide Pore particles featuring a 300 Å pore size in a 4.0 mm ID x 100 mm format. The 100 mm length provides enhanced resolving power compared to shorter columns while maintaining practical analysis times. The 10 µm particle size supports lower operating backpressure and allows higher flow rates when appropriate. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, analyte characteristics, and instrument configuration.
This column is commonly used for proteins, peptides, enzymes, natural products, and other larger polar or neutral compounds. It is frequently selected for USP L10 methods, biomolecule analysis, pharmaceutical development, and preparative method scouting involving larger molecules where alternative selectivity is desired.
Key Benefits
RP Cyano Wide Pore stationary phase
USP L10 column equivalent chemistry
Cyanopropyl bonded phase
300 Å pore size for larger molecules
High-purity silica support
Alternative selectivity to C18 columns
Faster equilibration than many traditional reversed-phase columns
Reduced hydrophobic retention
Suitable for polar and neutral compounds
Excellent for biomolecule separations and method development
Typical Applications
USP L10 methods
Peptide analysis
Protein separations
Enzyme analysis
Natural product analysis
Pharmaceutical analysis
Biomolecule characterization
Method development
Preparative method scouting
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: RP Cyano Wide Pore
USP Classification: L10
Chromatography Mode: Reversed Phase
Bonded Phase: Cyanopropyl (CN)
Endcapping: Not Endcapped
Particle Size: 10 µm
Pore Size: 300 Å
Column Dimensions: 4.0 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Packed and shipped in reversed-phase solvents
Wide pore design improves accessibility for proteins, peptides, enzymes, and other larger molecules
Increased column length provides improved resolution compared to shorter formats
Frequently selected for USP L10 methods involving larger analytes
Suitable for preparative method scouting and method transfer studies
This is a custom manufactured item and cannot be canceled or returned once ordered