HPLC Column, RP Cyano, 10um, 4.0mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Cyano is a versatile reversed-phase stationary phase designed for HPLC methods requiring lower hydrophobic retention, rapid equilibration, and selectivity different from traditional C18 columns. Manufactured using high-purity silica with a cyanopropyl (CN) bonded phase, it provides balanced retention for polar and moderately hydrophobic compounds while serving as an effective alternative for USP L10 methods. The unique cyano functionality often delivers different separation characteristics than alkyl-bonded phases, making it valuable for method development and selectivity screening.
68034-15P-4 is an analytical HPLC column packed with 10 µm RP Cyano particles featuring a 100 Å pore size in a 4.0 mm ID x 150 mm format. The 150 mm column length provides enhanced resolving power and peak capacity compared to shorter formats while maintaining practical run times. The 10 µm particle size supports lower operating backpressure and allows higher flow rates when appropriate. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, analyte characteristics, and instrument configuration.
This column is commonly used for polar and neutral compounds where reduced retention and faster equilibration are desirable. It is frequently selected for USP L10 methods, pharmaceutical analysis, impurity profiling, quality control testing, and method development projects requiring alternative reversed-phase selectivity.
Key Benefits
RP Cyano stationary phase
USP L10 column equivalent chemistry
Cyanopropyl bonded phase
High-purity silica support
Alternative selectivity to C18 columns
Faster equilibration than many traditional reversed-phase columns
Reduced hydrophobic retention
Suitable for polar and neutral compounds
Lower operating backpressure with 10 µm particles
Excellent for method development and selectivity screening
Typical Applications
USP L10 methods
Pharmaceutical analysis
Impurity profiling
Method development
Quality control testing
Polar compound analysis
Neutral compound analysis
Alternative selectivity screening
Routine HPLC analysis
Preparative method scouting
Specifications
Product Type: HPLC Column
Stationary Phase: RP Cyano
USP Classification: L10
Chromatography Mode: Reversed Phase
Bonded Phase: Cyanopropyl (CN)
Endcapping: Not Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.0 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Packed and shipped in reversed-phase solvents
Commonly used as an alternative selectivity choice to traditional C18 columns
Longer column length provides improved resolution and peak capacity
Frequently selected for USP L10 methods
Useful for preparative method scouting and method transfer studies
This is a custom manufactured item and cannot be canceled or returned once ordered