Guard Column Cartridges, RP Cyano Wide Pore, 10 um, 300 A. 4.0 mm ID x 10 mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent RP Cyano Wide Pore Guard Column Cartridges are packed with the same cyanopropyl (CN) bonded stationary phase used in Cogent RP Cyano Wide Pore analytical columns. Manufactured with high-purity silica and a 3-carbon linker terminated with a cyano functional group, these guard cartridges provide the same USP L10 selectivity as the analytical column while protecting it from contamination and premature fouling. The 300 Å pore structure improves accessibility for larger molecules such as peptides, proteins, enzymes, and other biomolecules.

68034-PG2-3 is a guard column cartridge packed with 10 µm RP Cyano Wide Pore particles featuring a 300 Å pore size in a 4.0 mm ID x 10 mm format. Installed ahead of the analytical column, it captures particulates, strongly retained contaminants, and sample matrix components before they reach the primary analytical bed. This protection helps maintain chromatographic performance, improve reproducibility, and extend analytical column lifetime.

These guard cartridges are designed for use with 3.0 mm, 4.0 mm, and 4.6 mm ID Cogent RP Cyano Wide Pore analytical columns. Each cartridge is packed in reversed-phase solvent and housed in a stainless steel tube with stainless steel frits pressed into durable PEEK frit caps for reliable long-term performance.

Key Benefits

  • RP Cyano Wide Pore stationary phase

  • USP L10 column equivalent chemistry

  • Cyanopropyl bonded phase

  • 300 Å pore size for larger molecules

  • High-purity silica support

  • Not endcapped

  • Protects analytical columns from particulates and contaminants

  • Maintains chromatographic performance

  • Extends analytical column service life

  • Stainless steel cartridge construction with PEEK frit caps

Typical Applications

  • USP L10 methods

  • Peptide analysis

  • Protein separations

  • Enzyme analysis

  • Natural product analysis

  • Pharmaceutical analysis

  • Biomolecule characterization

  • Method development

  • Column protection

  • Sample cleanup prior to analytical separation

Specifications

  • Product Type: Guard Column Cartridges

  • Stationary Phase: RP Cyano Wide Pore

  • USP Classification: L10

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Cyanopropyl (CN)

  • Endcapping: Not Endcapped

  • Particle Size: 10 µm

  • Pore Size: 300 Å

  • Cartridge Dimensions: 4.0 mm ID x 10 mm

  • Hardware Material: Stainless Steel

  • Frit Material: Stainless Steel

  • End Caps: PEEK

  • Quantity: 5/PK

  • Brand: Cogent

Guard Column Holder Requirement

Additional Resources

Important Notes

  • Packed and shipped in reversed-phase solvent

  • Designed for use with 3.0 mm, 4.0 mm, and 4.6 mm ID RP Cyano Wide Pore analytical columns

  • Wide pore design improves accessibility for proteins, peptides, enzymes, and other larger molecules

  • Matching stationary phase chemistry helps maintain chromatographic selectivity

  • Recommended for routine analytical HPLC, biomolecule analysis, and USP L10 applications


 

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