UHPLC Column, RP Phenyl, 1.8um, 100A. 2.1mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl™ is a reversed-phase UHPLC stationary phase designed to provide enhanced selectivity for aromatic and structurally related compounds. Manufactured using a propyl linker with a terminal phenyl ring bonded to ultra-high purity silica and fully double end capped, this phase offers unique π-π interaction mechanisms that can improve separation of compounds that may be difficult to resolve on traditional alkyl phases. It is particularly useful for aromatic pharmaceuticals, positional isomers, flavonoids, tocopherols, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, and many natural products.
68124-10P-2 is a UHPLC column packed with 1.8 µm RP Phenyl™ particles featuring a 100 Å pore size in a 2.1 mm ID x 100 mm format. This is one of the most popular RP Phenyl™ column configurations due to its combination of high efficiency, reduced solvent consumption, and excellent compatibility with LC-MS instrumentation. The 100 mm length provides increased resolution and peak capacity compared to shorter column formats, while the sub-2 µm particle technology delivers outstanding chromatographic performance. Typical operating flow rates are approximately 0.2–0.4 mL/min. Because of the low flow rates required by 2.1 mm ID columns, any HPLC system used with this column must be capable of accurate and reproducible low-flow operation.
Designed specifically for high-pressure UHPLC applications, this column provides maximum performance when used on UHPLC systems capable of handling the elevated pressures produced by 1.8 µm particles. It is an excellent choice for LC-MS methods, aromatic compounds, positional isomers, pharmaceutical analysis, and complex sample matrices requiring enhanced selectivity and high resolution.
Key Benefits
RP Phenyl™ stationary phase
Fully double end capped
Propyl phenyl bonded phase
Ultra-high purity silica support
Enhanced aromatic selectivity
π-π interaction capability
Designed for UHPLC applications
High-efficiency 1.8 µm particles
Ideal for LC-MS methods
Reduced solvent consumption
Typical Applications
LC-MS methods
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
API analysis
Natural product analysis
Pharmaceutical method development
UHPLC analysis
Specifications
Product Type: UHPLC Column
Stationary Phase: RP Phenyl™
Chromatography Mode: Reversed Phase
Bonded Phase: Propyl Phenyl
Endcapping: Fully Double End Capped
Particle Size: 1.8 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 0.2–0.4 mL/min
Brand: Cogent
Important Notes
Specifically designed for UHPLC operation and high-pressure reversed-phase chromatography
Delivers maximum performance when used on a UHPLC system designed for sub-2 µm particle columns
May be used on compatible HPLC systems only if instrument pressure limits are not exceeded and low-flow operation is reliable
Sub-2 µm particles generate significantly higher backpressure than conventional HPLC columns
The 2.1 mm ID format is commonly used for LC-MS applications
Standard HPLC systems must be capable of precise and reproducible operation at approximately 0.2–0.4 mL/min
The 100 mm length provides greater resolution and peak capacity than 50 mm columns
Enhanced selectivity for aromatic and phenyl-containing compounds compared to traditional alkyl phases
Samples should be filtered through a 0.2 µm syringe filter prior to injection