UHPLC Column, RP Phenyl Hexyl, 1.8um, 100A. 4.6mm ID x 50mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent Phenyl Hexyl™ is a reversed-phase UHPLC stationary phase designed to provide enhanced selectivity for aromatic and moderately hydrophobic compounds. Manufactured with a phenyl ring attached through a six-carbon linker and fully double end capped on ultra-high purity silica, this phase offers strong π-π interactions while minimizing the influence of residual silanol activity. The extended C6 linker can provide different selectivity than traditional Phenyl phases, making it particularly useful for aromatic analytes, positional isomers, pharmaceutical compounds, flavonoids, tocopherols, and natural products.

68139-05P is a UHPLC column packed with 1.8 µm Phenyl Hexyl™ particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm format. The short 50 mm length is optimized for rapid separations and high-throughput analytical workflows, while the sub-2 µm particle technology provides exceptional efficiency, high peak capacity, and excellent chromatographic performance. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on mobile phase composition, temperature, and instrument pressure limitations.

This column is specifically engineered for high-pressure UHPLC applications and is ideal for aromatic compounds requiring enhanced selectivity and efficient separations. Methanol is often preferred over acetonitrile when maximizing π-π interactions is desired. While compatible HPLC systems may be used if pressure limits allow, this column is designed primarily for UHPLC operation where the benefits of sub-2 µm particle technology can be fully realized.

Key Benefits

  • Phenyl Hexyl™ stationary phase

  • Fully double end capped

  • Six-carbon linker with terminal phenyl group

  • Ultra-high purity silica support

  • Enhanced π-π interaction selectivity

  • Designed for UHPLC applications

  • High-efficiency 1.8 µm particles

  • Fast analysis times

  • Excellent for aromatic compounds

  • Reduced solvent consumption

Typical Applications

  • Aromatic compound analysis

  • Positional isomer separations

  • Tocopherol analysis

  • Flavonoid analysis

  • Polynuclear aromatic hydrocarbon analysis

  • Nitro-aromatic compound analysis

  • API analysis

  • Natural product analysis

  • Pharmaceutical method development

  • UHPLC analysis

Specifications

  • Product Type: UHPLC Column

  • Stationary Phase: Phenyl Hexyl™

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Phenyl Hexyl

  • Endcapping: Fully Double End Capped

  • Particle Size: 1.8 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 50 mm

  • Length: 50 mm

  • Typical Flow Rate: 1.0–2.0 mL/min

  • Brand: Cogent

Important Notes

  • Designed specifically for UHPLC operation and high-pressure reversed-phase chromatography

  • 1.8 µm particles generate substantially higher backpressure than conventional HPLC columns

  • Maximum performance is achieved on UHPLC systems designed for sub-2 µm particle technology

  • May be used on compatible HPLC systems only if instrument pressure limits are not exceeded

  • Phenyl Hexyl chemistry may provide different selectivity than traditional Phenyl phases

  • Methanol may enhance π-π interactions compared to acetonitrile for certain applications

  • Excellent choice for aromatic compounds containing benzene rings

  • Samples should be filtered through a 0.2 µm syringe filter prior to injection


 

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