UHPLC Column, RP Phenyl Hexyl, 1.8um, 100A. 2.1mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent Phenyl Hexyl™ is a reversed-phase UHPLC stationary phase designed to provide enhanced selectivity for aromatic and moderately hydrophobic compounds. Manufactured with a phenyl ring attached through a six-carbon linker and fully double end capped on ultra-high purity silica, this phase offers strong π-π interactions while minimizing the influence of residual silanol activity. The extended C6 linker can provide different selectivity than traditional Phenyl phases, making it particularly useful for aromatic analytes, positional isomers, pharmaceutical compounds, flavonoids, tocopherols, and natural products.
68139-05P-2 is a UHPLC column packed with 1.8 µm Phenyl Hexyl™ particles featuring a 100 Å pore size in a 2.1 mm ID x 50 mm format. The narrow-bore design reduces solvent consumption and is frequently selected for LC-MS applications. The short 50 mm length is optimized for rapid separations and high-throughput analytical workflows, while the sub-2 µm particle technology provides exceptional efficiency and peak capacity. Typical operating flow rates are approximately 0.2–0.4 mL/min. Because of the low flow rates required by 2.1 mm ID columns, standard HPLC systems must be capable of precise and reproducible low-flow operation if they are used with this column.
This column is specifically engineered for high-pressure UHPLC applications and is ideal for aromatic compounds requiring enhanced selectivity, fast analysis times, and efficient separations. Methanol is often preferred over acetonitrile when maximizing π-π interactions is desired. While compatible HPLC systems may be used if pressure limits allow, this column is designed primarily for UHPLC operation where the benefits of sub-2 µm particle technology can be fully realized.
Key Benefits
Phenyl Hexyl™ stationary phase
Fully double end capped
Six-carbon linker with terminal phenyl group
Ultra-high purity silica support
Enhanced π-π interaction selectivity
Designed for UHPLC applications
High-efficiency 1.8 µm particles
Fast analysis times
Ideal for LC-MS methods
Reduced solvent consumption
Typical Applications
LC-MS methods
Aromatic compound analysis
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
API analysis
Natural product analysis
Pharmaceutical method development
Specifications
Product Type: UHPLC Column
Stationary Phase: Phenyl Hexyl™
Chromatography Mode: Reversed Phase
Bonded Phase: Phenyl Hexyl
Endcapping: Fully Double End Capped
Particle Size: 1.8 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 0.2–0.4 mL/min
Brand: Cogent
Important Notes
Designed specifically for UHPLC operation and high-pressure reversed-phase chromatography
1.8 µm particles generate substantially higher backpressure than conventional HPLC columns
Maximum performance is achieved on UHPLC systems designed for sub-2 µm particle technology
The 2.1 mm ID format is commonly used for LC-MS applications
Standard HPLC systems must be capable of precise and reproducible operation at approximately 0.2–0.4 mL/min
Phenyl Hexyl chemistry may provide different selectivity than traditional Phenyl phases
Methanol may enhance π-π interactions compared to acetonitrile for certain applications
Excellent choice for aromatic compounds containing benzene rings
Samples should be filtered through a 0.2 µm syringe filter prior to injection