Catalog Number - 68139-10P

Cogent Phenyl Hexyl™ is a reversed-phase UHPLC stationary phase designed to provide enhanced selectivity for aromatic and moderately hydrophobic compounds. Manufactured with a phenyl ring attached through a six-carbon linker and fully double end capped on ultra-high purity silica, this phase offers strong π-π interactions while minimizing the influence of residual silanol activity. The extended C6 linker provides different selectivity compared to traditional Phenyl phases, making it especially useful for aromatic analytes, positional isomers, pharmaceutical compounds, flavonoids, tocopherols, and natural products.

68139-10P is a UHPLC column packed with 1.8 µm Phenyl Hexyl™ particles featuring a 100 Å pore size in a 4.6 mm ID x 100 mm format. The 100 mm column length provides increased resolution and peak capacity compared to shorter 50 mm columns, while the sub-2 µm particle technology delivers exceptional efficiency and chromatographic performance. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on method conditions and instrument pressure limitations.

Specifically engineered for high-pressure UHPLC applications, this column is ideal for aromatic compounds requiring enhanced selectivity and improved separation performance. Methanol is often preferred over acetonitrile when maximizing π-π interactions is desired. While compatible HPLC systems may be used if pressure limits permit, this column is designed primarily for UHPLC operation where the full benefits of sub-2 µm particle technology can be realized.

Key Benefits

• Phenyl Hexyl™ stationary phase

• Fully double end capped

• Six-carbon linker with terminal phenyl group

• Ultra-high purity silica support

• Enhanced π-π interaction selectivity

• Designed for UHPLC applications

• High-efficiency 1.8 µm particles

• Increased peak capacity

• Improved chromatographic resolution

• Excellent for aromatic compounds

Typical Applications

• Aromatic compound analysis

• Positional isomer separations

• Tocopherol analysis

• Flavonoid analysis

• Polynuclear aromatic hydrocarbon analysis

• Nitro-aromatic compound analysis

• API analysis

• Natural product analysis

• Pharmaceutical method development

• Complex sample separations

Specifications

• Product Type: UHPLC Column

• Stationary Phase: Phenyl Hexyl™

• Chromatography Mode: Reversed Phase

• Bonded Phase: Phenyl Hexyl

• Endcapping: Fully Double End Capped

• Particle Size: 1.8 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 100 mm

• Length: 100 mm

• Typical Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Designed specifically for UHPLC operation and high-pressure reversed-phase chromatography

• 1.8 µm particles generate substantially higher backpressure than conventional HPLC columns

• Maximum performance is achieved on UHPLC systems designed for sub-2 µm particle technology

• May be used on compatible HPLC systems only if instrument pressure limits are not exceeded

• The 100 mm length provides greater resolution and peak capacity than 50 mm columns

• Phenyl Hexyl chemistry may provide different selectivity than traditional Phenyl phases

• Methanol may enhance π-π interactions compared to acetonitrile for certain applications

• Excellent choice for aromatic compounds containing benzene rings

• Samples should be filtered through a 0.2 µm syringe filter prior to injection

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